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pro vyhledávání: '"Jeffrey A. Goliger"'
Autor:
Jeffrey A. Goliger, David L. Paul
Publikováno v:
Developmental Dynamics. 200:1-13
To elucidate mechanisms underlying gap junction-mediated intercellular communication in epidermal keratinocytes, we have examined the expression of four connexin genes, Cx26, Cx31.1, Cx37, and Cx43, in fetal (embryonic day 17–18), newborn (post-nat
Publikováno v:
Annual review of biochemistry. 65
Cells in tissues share ions, second messengers, and small metabolites through clusters of intercellular channels called gap junctions. This type of intercellular communication permits coordinated cellular activity. Intercellular channels are formed f
Autor:
David L. Paul, Jeffrey A. Goliger
Publikováno v:
Molecular biology of the cell. 6(11)
We show that connexin expression and in vivo patterns of communication were dramatically altered in response to epidermal wounding. Six hours after injury, Cx26 was up-regulated in the differentiated cells proximal to the wound, but was down-regulate
Publikováno v:
Digestive Diseases and Sciences. 43:1493-1493
Publikováno v:
Journal of Molecular Biology. 205:331-341
We have constructed novel transcription templates in which we have fused the late gene promoters of Escherichia coli phages lambda and 82 upstream from three different rho-independent transcription terminators. Using an in vitro transcription assay a
Autor:
Jeffrey A. Goliger, Jeffrey W. Roberts
Publikováno v:
Journal of Molecular Biology. 210:461-471
The gene Q antiterminator proteins of phages λ and 82 modify RNA polymerase at sites (named qut ) that are close to, and apparently inseparable from the promoters themselves. Modification occurs while RNA polymerase has paused close to the start sit
Publikováno v:
Journal of Molecular Biology. 210:453-460
Lambdoid phage late gene operons are positively regulated by genome-specific antiterminator proteins encoded by the Q gene of each phage. In this paper, we compare the activity of phage λ and phage 82 Q proteins. Q 82 -mediated antitermination, like
Autor:
Jeffrey W. Roberts, Jeffrey A. Goliger
Publikováno v:
Journal of Biological Chemistry. 262:11721-11725
Phage 82 gene Q encodes a phage-specific positive regulator of late gene expression, thought, by analogy to the corresponding gene of phage lambda, to be a transcription antiterminator. We have cloned and sequenced the phage 82 gene Q and have overpr