Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeffrey A. Dvergsten"'
Autor:
Cory Stingl, Jeffrey A. Dvergsten, Simon W. M. Eng, Rae S. M. Yeung, Marvin J. Fritzler, Thomas Mason, Cynthia Crowson, Deepak Voora, Ann M. Reed
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 8, Pp 671-681 (2022)
Objective The study objective was to identify differences in gene expression between treatment responders (TRs) and treatment non‐responders (TNRs) diagnosed with juvenile dermatomyositis (JDM). Methods Gene expression analyses were performed using
Externí odkaz:
https://doaj.org/article/2eb17506c6c343138e40c5679d1dae1c
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Calcinosis, or the deposition of insoluble calcium salts in the skin, subcutaneous tissue, fascia, tendons, and muscles, is a feared complication of juvenile dermatomyositis. Calcinosis is estimated to affect up to 40% of patients with juvenile derma
Externí odkaz:
https://doaj.org/article/49634182e3f442b2b50bcac6c2d56a53
Autor:
Ian D. Ferguson, Patricia Griffin, Joshua J. Michel, Hiroshi Yano, Sarah L. Gaffen, Robert G. Mueller, Jeffrey A. Dvergsten, Jon D. Piganelli, Margalit E. Rosenkranz, Daniel A. Kietz, Abbe N. Vallejo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T cells are considered autoimmune effectors in juvenile idiopathic arthritis (JIA), but the antigenic cause of arthritis remains elusive. Since T cells comprise a significant proportion of joint-infiltrating cells, we examined whether the environment
Externí odkaz:
https://doaj.org/article/757c2d5e02994195bbce2ee52debeb3b
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Humans have an innate desire to observe and subsequently dissect an event into component pieces in an effort to better characterize the event. We then examine these pieces individually and in combinations using this information to determine the outco
Externí odkaz:
https://doaj.org/article/10fc111de2b54a08b7de1312f1866268
Autor:
Kim M. Huffman, Ann M. Reed, David S. Pisetsky, Lawrence R. Landerman, Olga Ilkayeva, Jeffrey A. Dvergsten
Publikováno v:
Rheumatology. 61:1699-1708
Objectives To perform an exploratory study to identify a JDM serum metabolic profile that differs from healthy controls (HCs) and responds to immunosuppressive treatment. Methods Blood was collected from 9 HCs and 10 patients diagnosed with probable
Autor:
Dawn M. Wahezi, George Tomlinson, Sarah Ringold, Megan L. Curran, Ann M. Reed, Kuan Liu, Lawrence Jung, Kelly A. Rouster-Steven, Melissa S Tesher, Brian M. Feldman, Olli Saarela, Adam M. Huber, Sharon Bout-Tabaku, Susan Kim, Jeffrey A. Dvergsten, Barbara A. Eberhard
Publikováno v:
The Journal of rheumatology. 48(1)
Objectives.To determine the feasibility of comparing the Childhood Arthritis and Rheumatology ResearchAlliance (CARRA) consensus treatment plans (CTP) in treating moderate new-onset juvenile dermatomyositis (JDM) using the CARRA registry, and to esta
Publikováno v:
The Journal of Rheumatology. 47:479-479
In adults, there is an established correlation between dermatomyositis (DM) and malignancy1, but in children there are very few case reports in the literature. Here we report 2 cases from our institution of development of leukemia after diagnosis of
Autor:
Allyson Pishko, Patricia Griffin, Jeffrey A. Dvergsten, Margalit Rosenkranz, Robert G. Mueller, Ann M. Reed, Abbe N. Vallejo, Joshua Michel, Daniel Kietz, Sameem Abedin
Publikováno v:
Arthritis & Rheumatism. 65:2201-2210
Objective CD8+ T cells lacking CD28 were originally reported to be a characteristic feature of juvenile idiopathic arthritis (JIA), but the relevance of these unusual cells to this disease remains to be elucidated. Because of recent evidence that los
Autor:
Amy P.N. Skubitz, Mark E. Rosenberg, David Chmielewski, Jeffrey A. Dvergsten, John R. Silkensen, J. C. Manivel, Keith M. Skubitz
Publikováno v:
Journal of Clinical Investigation. 96:2646-2653
The function of clusterin, a heterodimeric glycoprotein markedly induced in renal and other organ injuries, is unclear. Since renal injury is accompanied by alterations in cell attachment, it is possible that clusterin functions to promote cell-cell
Publikováno v:
Kidney International. (3):828-835
Expression of clusterin in human renal diseases. Clusterin, a glycoprotein with potent cohesive properties, is induced in a wide variety of acute and chronic experimental renal diseases. The purpose of this study was to examine clusterin expression i