Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jeffrey A. Bryant"'
Autor:
Jeffrey D. Bryant, Jennifer S. Lee, Ana De Almeida, Judy Jacques, Ching-Hung Chang, William Fassler, Christophe Quéva, Lorena Lerner, Edward M. Kennedy
Publikováno v:
Molecular Therapy: Oncolytics, Vol 28, Iss , Pp 321-333 (2023)
Oncolytic viruses (OVs) promote the anti-tumor immune response as their replication, and the subsequent lysis of tumor cells, triggers the activation of immune-sensing pathways. Arming OVs by expressing transgenes with the potential to promote immune
Externí odkaz:
https://doaj.org/article/6e132b86ae2548e58758a33bef8f6084
Autor:
Edward M. Kennedy, Agnieszka Denslow, Jacqueline Hewett, Lingxin Kong, Ana De Almeida, Jeffrey D. Bryant, Jennifer S. Lee, Judy Jacques, Sonia Feau, Melissa Hayes, Elizabeth L. McMichael, Daniel Wambua, Terry Farkaly, Amal A Rahmeh, Lauren Herschelman, Danielle Douglas, Jacob Spinale, Sanmit Adhikari, Jessica Deterling, Matt Scott, Brian B. Haines, Mitchell H. Finer, Ted T Ashburn, Christophe Quéva, Lorena Lerner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The development of neutralizing antibodies can limit the therapeutic effectiveness of systemically administered oncolytic viruses (OV). Here, to enable repeated intravenous administration, the authors report the development of synthetic RNA viruses f
Externí odkaz:
https://doaj.org/article/e35ea397d9ba41b5b30d0dfa85eb8713
Publikováno v:
Science Advances
CReP recruits translation machinery to the ER and promotes local translation during global protein synthesis repression.
Eukaryotic protein synthesis control at multiple levels allows for dynamic, selective responses to diverse conditions, but s
Eukaryotic protein synthesis control at multiple levels allows for dynamic, selective responses to diverse conditions, but s
Publikováno v:
The CDC Field Epidemiology Manual
Domestically and internationally, Emergency Operation Centers and Incident Management Systems provide a structure and framework to coordinate preparedness and response activities. This chapter provides a US perspective on emergency response systems,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a276d86ba47e88c9bc9e0a750a76a2da
https://doi.org/10.1093/oso/9780190933692.003.0016
https://doi.org/10.1093/oso/9780190933692.003.0016
Autor:
Benjamin McMahon, Maccabe Andrew C, Kunaal Boal, Daniel Fontaine, Jeffrey F. Bryant, Nicholas Campbell, Timothy M. Dresser, Randall Lapierre
Publikováno v:
2018 IEEE International Symposium on Antennas and Propagation & USNC/URSI National Radio Science Meeting.
The need for disruptive advances in warfighter capability, upgradability, and utilization drives sensor systems toward convergent RF functionality with shared resources. The reliance of modern federated RF systems on redundant hardware leads to under
Autor:
Michael C. Brown, Mikhail I. Dobrikov, Elena Y. Dobrikova, Matthias Gromeier, Qing Zhang, Jeffrey D. Bryant, Sarah Gemberling
Publikováno v:
Molecular and cellular biology. 38(11)
Death-associated protein 5 (DAP5) is an atypical isoform of the translation initiation scaffolds eukaryotic initiation factor 4GI (eIF4GI) and eIF4GII (eIF4GI/II), which recruit mRNAs to ribosomes in mammals. Unlike eIF4GI/II, DAP5 binds eIF2β, a su
Autor:
Stephen T. Keir, Matthias Gromeier, Roger E. McLendon, Michaela Lefaivre, Eric S. Lipp, Darell D. Bigner, Jeffrey D. Bryant, Kathryn Perkinson, Hailan Piao, Vidyalakshmi Chandramohan
Publikováno v:
Archives of pathologylaboratory medicine. 141(12)
Context.— The oncolytic polio-rhinovirus recombinant (PVSRIPO) has demonstrated promise in currently ongoing phase I/II clinical trials against recurrent glioblastoma and was granted breakthrough therapy designation by the Food and Drug Administrat
Autor:
Janell Hostettler, Michelle L. Bowie, David M. Ashley, Darell D. Bigner, Jeffrey D. Bryant, Smita K. Nair, Matthias Gromeier, Michael C. Brown
Publikováno v:
Neuro-Oncology. 20:vi127-vi128
BACKGROUND: Stimulator of interferon genes (STING), a protein located in the endoplasmic reticulum, is a key mediator of innate immune response to non-CpG cytosolic DNA. Intact STING has been shown to be involved in the induction of the innate antitu
Autor:
Robert G. Griffin, Björn Corzilius, Paul P. Woskov, Albert A. Smith, Richard J. Temkin, Ronald DeRocher, Jeffrey A. Bryant
Publikováno v:
PMC
We described a versatile spectrometer designed for the study of dynamic nuclear polarization (DNP) at low temperatures and high fields. The instrument functions both as an NMR spectrometer operating at 212 MHz ([superscript 1]H frequency) with DNP ca