Zobrazeno 1 - 10
of 565
pro vyhledávání: '"Jeffrey A. Sosman"'
Autor:
Paolo A. Ascierto, Christian Blank, Alexander M. Eggermont, Claus Garbe, Jeffrey E. Gershenwald, Omid Hamid, Axel Hauschild, Jason J. Luke, Janice M. Mehnert, Jeffrey A. Sosman, Hussein A. Tawbi, Mario Mandalà, Alessandro Testori, Corrado Caracò, Iman Osman, Igor Puzanov
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract The Great Debate session at the 2022 Melanoma Bridge congress (December 1–3) featured counterpoint views from leading experts on five contemporary topics of debate in the management of melanoma. The debates considered the choice of anti-ly
Externí odkaz:
https://doaj.org/article/72b5639fd85f4c0aa3e6387485d98c32
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Immune checkpoint inhibitors (ICIs) have increasingly been the mainstay of treatment for numerous malignancies. However, due to their association with autoimmunity, ICIs have resulted in a variety of side effects that involve multiple organs includin
Externí odkaz:
https://doaj.org/article/517e94373a8e404db7b5de93e9ff9be2
Autor:
Alessia Cimadamore, Michael Hurwitz, Mark Stein, Sabina Signoretti, Jeffrey A Sosman, David F McDermott, Michael B Atkins, Naomi B Haas, Elizabeth R Plimack, Hans Hammers, Mehmet A Bilen, Moshe C Ornstein, David Einstein, Opeyemi A Jegede, Robert Alter, David J Peace, Thomas Denize, Catherine J Wu, David Braun, Paul J Catalano
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background To determine the efficacy and toxicity of nivolumab monotherapy in treatment-naïve patients with non-clear cell renal cell carcinoma (nccRCC) and the efficacy of nivolumab/ipilimumab salvage therapy in patients with tumors unresponsive to
Externí odkaz:
https://doaj.org/article/f31aca68bfec4407896225ae6d30cdbd
Autor:
Rebecca F. Halperin, Apurva Hegde, Jessica D. Lang, Elizabeth A. Raupach, C4RCD Research Group, Christophe Legendre, Winnie S. Liang, Patricia M. LoRusso, Aleksandar Sekulic, Jeffrey A. Sosman, Jeffrey M. Trent, Sampathkumar Rangasamy, Patrick Pirrotte, Nicholas J. Schork
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The robust detection of disease-associated splice events from RNAseq data is challenging due to the potential confounding effect of gene expression levels and the often limited number of patients with relevant RNAseq data. Here we present a
Externí odkaz:
https://doaj.org/article/a3220a92cf2645288aad59ed2f183636
Autor:
Paolo A. Ascierto, Michael B. Atkins, Alexander M. Eggermont, Jeffrey E. Gershenwald, Jean-Jacques Grob, Omid Hamid, Vernon K. Sondak, Jeffrey A. Sosman, Hussein A. Tawbi, Jeffrey S. Weber, Corrado Caracò, Iman Osman, Igor Puzanov
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract The Great Debate session at the 2020 Melanoma Bridge virtual congress (December 3rd–5th, Italy) featured counterpoint views from experts on five specific controversial issues in melanoma. The debates considered whether or not innate immuni
Externí odkaz:
https://doaj.org/article/a6ed1cc2e48e427fb2e3f34087eb34fc
Autor:
Andrew Haydon, Jessica C Hassel, Jeffrey A Sosman, Sunandana Chandra, Ryan Sullivan, Mario E Lacouture, Meghan J Mooradian, Alexander Menzies, Douglas B Johnson, Fei Ye, Prachi Bhave, Steven T Chen, Georgina Long, Briana Rose Halle, Farzana Y Zaman, Anna K Dewan, Rebecca Irlmeier, Paras Mehta, Nicholas R Kurtansky, Jacob S Choi, Tracey S Otto, Florentia Dimitriou, Veronica M Rotemberg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/2404ddf91eb64426ad24a0c1ae12dd85
Autor:
Rajeev Sharma, Laura C Cappelli, Michelle Turner, Julie R Brahmer, Jarushka Naidoo, Paolo Antonio Ascierto, Igor Puzanov, Hamzah Abu-Sbeih, Jeffrey A Sosman, Marc S Ernstoff, Jill Brufsky, Mario E Lacouture, Douglas B Johnson, Lamya Hamad, Miguel-Angel Perales, Eric Hansen, David E Gerber, Frank B Cortazar, Gregory A Masters, Michele Nanni, Satish P Shanbhag, Dimitra Skondra
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several cancers. While these immunotherapies have improved patient outcomes in many clinical settings, they bring accompanying risks of toxicity, specifically immune-re
Externí odkaz:
https://doaj.org/article/c417f1dc5cfc4fceb691f49dd249e32b
Autor:
Patricia M LoRusso, Aleksandar Sekulic, Jeffrey A Sosman, Winnie S Liang, John Carpten, David W Craig, David B Solit, Alan H Bryce, Jeffrey A Kiefer, Jessica Aldrich, Sara Nasser, Rebecca Halperin, Sara A Byron, Mary Jo Pilat, Scott A Boerner, Diane Durecki, William P D Hendricks, Daniel Enriquez, Tyler Izatt, Jonathan Keats, Christophe Legendre, Svetomir N Markovic, Amy Weise, Fatima Naveed, Jessica Schmidt, Gargi D Basu, Shobana Sekar, Jonathan Adkins, Erica Tassone, Karthigayini Sivaprakasam, Victoria Zismann, Valerie S Calvert, Emanuel F Petricoin, Leslie Anne Fecher, Christopher Lao, J Paul Eder, Nicholas J Vogelzang, Jane Perlmutter, Mark Gorman, Barbara Manica, Lisa Fox, Nicholas Schork, Daniel Zelterman, Michelle DeVeaux, Richard W Joseph, C Lance Cowey, Jeffrey M Trent
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248097 (2021)
Although combination BRAF and MEK inhibitors are highly effective for the 40-50% of cutaneous metastatic melanomas harboring BRAFV600 mutations, targeted agents have been ineffective for BRAFV600wild-type (wt) metastatic melanomas. The SU2C Genomics-
Externí odkaz:
https://doaj.org/article/ea286e5ad5d3466fb04534c8639561db
Autor:
J. Randall Patrinely, Ben McGuigan, Sunandana Chandra, Sarah E. Fenton, Akansha Chowdhary, Lucy B. Kennedy, Meghan J. Mooradian, Marisa Palmeri, Daniella Portal, Sara N. Horst, Elizabeth A. Scoville, Georgina V. Long, Chanjuan Shi, Janice M. Mehnert, Ryan J. Sullivan, April K. Salama, Jeffrey A. Sosman, Alexander M. Menzies, Douglas B. Johnson
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Immune checkpoint inhibitors (ICI) predispose patients to immune-related adverse events (irAEs). Although hepatitis is a potentially lethal toxicity, the timing and outcomes have not been well described. In this retrospective study, patients from six
Externí odkaz:
https://doaj.org/article/de26ed8c2f814f73ad812c4ee03fc68d
Autor:
Sapna P. Patel, Megan Othus, Yuanbin Chen, G. Paul Wright, Kathleen J. Yost, John R. Hyngstrom, Siwen Hu-Lieskovan, Christopher D. Lao, Leslie A. Fecher, Thach-Giao Truong, Jennifer L. Eisenstein, Sunandana Chandra, Jeffrey A. Sosman, Kari L. Kendra, Richard C. Wu, Craig E. Devoe, Gary B. Deutsch, Aparna Hegde, Maya Khalil, Ankit Mangla, Amy M. Reese, Merrick I. Ross, Andrew S. Poklepovic, Giao Q. Phan, Adedayo A. Onitilo, Demet G. Yasar, Benjamin C. Powers, Gary C. Doolittle, Gino K. In, Niels Kokot, Geoffrey T. Gibney, Michael B. Atkins, Montaser Shaheen, James A. Warneke, Alexandra Ikeguchi, Jose E. Najera, Bartosz Chmielowski, Joseph G. Crompton, Justin D. Floyd, Eddy Hsueh, Kim A. Margolin, Warren A. Chow, Kenneth F. Grossmann, Eliana Dietrich, Victor G. Prieto, Michael C. Lowe, Elizabeth I. Buchbinder, John M. Kirkwood, Larissa Korde, James Moon, Elad Sharon, Vernon K. Sondak, Antoni Ribas
Publikováno v:
New England Journal of Medicine. 388:813-823
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::572c5454e442063325a108f2b1da3b9a
https://doi.org/10.1056/nejmoa2211437
https://doi.org/10.1056/nejmoa2211437