Zobrazeno 1 - 10
of 653
pro vyhledávání: '"Jeffrey A Morgan"'
Autor:
Chandrajit P Raut, Yves Boucher, Dan G Duda, Jeffrey A Morgan, Richard Quek, Marek Ancukiewicz, Johanna Lahdenranta, J Paul Eder, George D Demetri, Rakesh K Jain
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e26331 (2012)
Sorafenib is a multi-targeted tyrosine kinase inhibitor with therapeutic efficacy in several malignancies. Sorafenib may exert its anti-neoplastic effect in part by altering vascular permeability and reducing intra-tumoral interstitial hypertension.
Externí odkaz:
https://doaj.org/article/60a28fac75ca4f6a85b43605694a62b8
Autor:
Simon Pollett, Michael A Johansson, Nicholas G Reich, David Brett-Major, Sara Y Del Valle, Srinivasan Venkatramanan, Rachel Lowe, Travis Porco, Irina Maljkovic Berry, Alina Deshpande, Moritz U G Kraemer, David L Blazes, Wirichada Pan-Ngum, Alessandro Vespigiani, Suzanne E Mate, Sheetal P Silal, Sasikiran Kandula, Rachel Sippy, Talia M Quandelacy, Jeffrey J Morgan, Jacob Ball, Lindsay C Morton, Benjamin M Althouse, Julie Pavlin, Wilbert van Panhuis, Steven Riley, Matthew Biggerstaff, Cecile Viboud, Oliver Brady, Caitlin Rivers
Publikováno v:
PLoS Medicine, Vol 20, Iss 11, p e1004316 (2023)
[This corrects the article DOI: 10.1371/journal.pmed.1003793.].
Externí odkaz:
https://doaj.org/article/799a3c14bdd64878b8cf74e1201b7135
Publikováno v:
Mathematics in Applied Sciences and Engineering, Vol 2, Iss 4, Pp 290-309 (2021)
A mathematical model incorporating diffusion is developed to describe the spatial spread of COVID-19 epidemics in geographical regions. The dynamics of the spatial spread are based on community transmission of the virus. The model is applied to the o
Externí odkaz:
https://doaj.org/article/de329593d89e460a85450c672de40403
Autor:
G. Guy Bushkin, David Pincus, Jeffrey T. Morgan, Kris Richardson, Caroline Lewis, Sze Ham Chan, David P. Bartel, Gerald R. Fink
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Ime4p is a yeast N6-methyladenosine (m6A) methyltransferase with an unknown role in meiosis. Rme1p is a repressor of meiosis. Here the authors show that Ime4p methylates RME1 3′ UTR to reduce its expression and enable meiosis, thus providing an exa
Externí odkaz:
https://doaj.org/article/4227ec2b4c764d77808e435df040b4f0
Autor:
Sara M Nowinski, Ashley Solmonson, Scott F Rusin, J Alan Maschek, Claire L Bensard, Sarah Fogarty, Mi-Young Jeong, Sandra Lettlova, Jordan A Berg, Jeffrey T Morgan, Yeyun Ouyang, Bradley C Naylor, Joao A Paulo, Katsuhiko Funai, James E Cox, Steven P Gygi, Dennis R Winge, Ralph J DeBerardinis, Jared Rutter
Publikováno v:
eLife, Vol 9 (2020)
Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In contrast to FASN, mtFAS is poorly characterized, especially in higher eukaryotes, with the major
Externí odkaz:
https://doaj.org/article/f28d705b3f05490b91c7e479d58b568b
Autor:
Agnieszka Sulima, Fuying Li, Jeffrey Brian Morgan, Phong Truong, Joshua F. G. Antoline, Therese Oertel, Rodell C. Barrientos, Oscar B. Torres, Zoltan Beck, Gregory H. Imler, Jeffrey R. Deschamps, Gary R. Matyas, Arthur E. Jacobson, Kenner C. Rice
Publikováno v:
Molecules, Vol 27, Iss 5, p 1553 (2022)
In our continuing effort to develop effective anti-heroin vaccines as potential medications for the treatment of opioid use disorder, herein we present the design and synthesis of the haptens: 1-AmidoMorHap (1), 1-AmidoMorHap epimer (2), 1 Amido-Dihy
Externí odkaz:
https://doaj.org/article/7dcc4f534c6c4cc6b767b5b5ab286a1c
Autor:
Inga-Marie Schaefer, Matthew L. Hemming, Meijun Z. Lundberg, Matthew P. Serrata, Isabel Goldaracena, Ninning Liu, Peng Yin, Joao A. Paulo, Steven P. Gygi, Suzanne George, Jeffrey A. Morgan, Monica M. Bertagnolli, Ewa T. Sicinska, Chen Chu, Shanshan Zheng, Adrian Mariño-Enríquez, Jason L. Hornick, Chandrajit P. Raut, Wen-Bin Ou, George D. Demetri, Sinem K. Saka, Jonathan A. Fletcher
Publikováno v:
British Journal of Cancer. 127:2072-2085
Advanced gastrointestinal stromal tumour (GIST) is characterised by genomic perturbations of key cell cycle regulators. Oncogenic activation of CDK4/6 results in RB1 inactivation and cell cycle progression. Given that single-agent CDK4/6 inhibitor th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99728f31140a073b466bed2211d43e19
https://doi.org/10.1038/s41416-022-01990-5
https://doi.org/10.1038/s41416-022-01990-5
Publikováno v:
Management Teaching Review. 8:152-169
We describe a short, interactive case-based activity for illustrating cognitive distortions of communication underlying resistance to change. Based on a real-life story, the case describes a failed effort by the mayor of Toowoomba, Australia to fund
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::297d443deb404c4fb3d5454d2052bc7f
https://doi.org/10.1177/23792981221076794
https://doi.org/10.1177/23792981221076794
Autor:
Pei-Ying Kobres, Jean-Paul Chretien, Michael A Johansson, Jeffrey J Morgan, Pai-Yei Whung, Harshini Mukundan, Sara Y Del Valle, Brett M Forshey, Talia M Quandelacy, Matthew Biggerstaff, Cecile Viboud, Simon Pollett
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 10, p e0007451 (2019)
IntroductionEpidemic forecasting and prediction tools have the potential to provide actionable information in the midst of emerging epidemics. While numerous predictive studies were published during the 2016-2017 Zika Virus (ZIKV) pandemic, it remain
Externí odkaz:
https://doaj.org/article/1c08ee27b7d3461ba6b4f30cad580c98
Autor:
Suzanne George, Jonathan A. Fletcher, Cloud P. Paweletz, Victor E. Velculescu, George D. Demetri, Andrew J. Wagner, Adrián Mariño-Enríquez, Olivia Triplett, Jillian Phallen, Constance M. Barysauskas, Jeffrey A. Morgan, Yanan Kuang, Alessandro Leal, César Serrano
Sunitinib (A) and Regorafenib (B) plasma concentration (ng/mL) across several timepoints during cycle 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0979e821099c659660359bfe544ca411
https://doi.org/10.1158/1078-0432.22475288.v1
https://doi.org/10.1158/1078-0432.22475288.v1
