Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jeffrey A Lyon"'
Autor:
Bernhards R Ogutu, Odika J Apollo, Denise McKinney, Willis Okoth, Joram Siangla, Filip Dubovsky, Kathryn Tucker, John N Waitumbi, Carter Diggs, Janet Wittes, Elissa Malkin, Amanda Leach, Lorraine A Soisson, Jessica B Milman, Lucas Otieno, Carolyn A Holland, Mark Polhemus, Shon A Remich, Christian F Ockenhouse, Joe Cohen, W Ripley Ballou, Samuel K Martin, Evelina Angov, V Ann Stewart, Jeffrey A Lyon, D Gray Heppner, Mark R Withers, MSP-1 Malaria Vaccine Working Group
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4708 (2009)
The antigen, falciparum malaria protein 1 (FMP1), represents the 42-kDa C-terminal fragment of merozoite surface protein-1 (MSP-1) of the 3D7 clone of P. falciparum. Formulated with AS02 (a proprietary Adjuvant System), it constitutes the FMP1/AS02 c
Externí odkaz:
https://doaj.org/article/656dad9481c241c485519a092be610e9
Autor:
Jeffrey A Lyon, Evelina Angov, Michael P Fay, JoAnn S Sullivan, Autumn S Girourd, Sally J Robinson, Elke S Bergmann-Leitner, Elizabeth H Duncan, Christian A Darko, William E Collins, Carole A Long, John W Barnwell
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2830 (2008)
Vaccination with Plasmodium falciparum MSP1(42)/complete Freund's adjuvant (FA) followed by MSP1(42)/incomplete FA is the only known regimen that protects Aotus nancymaae monkeys against infection by erythrocytic stage malaria parasites. The role of
Externí odkaz:
https://doaj.org/article/a17a050ee9564822bfb6f7a59cc4302a
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2189 (2008)
Synonymous codon replacement can change protein structure and function, indicating that protein structure depends on DNA sequence. During heterologous protein expression, low expression or formation of insoluble aggregates may be attributable to diff
Externí odkaz:
https://doaj.org/article/63bc402c9cde4d6499cee17d30938bfc
Autor:
Jeffrey (Kapali) Lyon
Publikováno v:
Mormon Studies Review. 9:139-145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eed6574f00e88d38d989790bdc339803
https://doi.org/10.5406/21568030.9.1.19
https://doi.org/10.5406/21568030.9.1.19
Autor:
Russell J. Howard, Stephen B. Aley, James A. Sherwood, Masamichi Aikawa, F W Klotz, Allan Saul, Jeffrey A. Lyon, Shigehiko Uni, Kevin Marsh, Lindsey J. Panton
Publikováno v:
The Journal of Cell Biology
The profound changes in the morphology, antigenicity, and functional properties of the host erythrocyte membrane induced by intraerythrocytic parasites of the human malaria Plasmodium falciparum are poorly understood at the molecular level. We have u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85da858846492b19ab1e3595b16e189c
https://ora.ox.ac.uk/objects/uuid:2af4c600-70b4-46b7-8a38-f8f5e89a458a
https://ora.ox.ac.uk/objects/uuid:2af4c600-70b4-46b7-8a38-f8f5e89a458a
Autor:
Evelina Angov, Elizabeth H. Duncan, Farhat Khan, Elke S. Bergmann-Leitner, Carole A. Long, Jeffrey A. Lyon, Gregory E. D. Mullen, John Robert Burge
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 75:437-442
Antibodies are thought to be the primary immune effectors in the defense against erythrocytic stage Plasmodium falciparum. Thus, malaria vaccines directed to blood stages of infection are evaluated based on their ability to induce antibodies with ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::979ad03876c4b1f551856960a7744dc0
https://doi.org/10.4269/ajtmh.2006.75.437
https://doi.org/10.4269/ajtmh.2006.75.437
Autor:
Gary Marit, Kent E. Kester, Jeffrey A. Lyon, Douglas S. Walsh, V. Ann Stewart, Joe Cohen, Nelly Kolodny, Pongsri Tongtawe, D. Gray Heppner, Panita Gosi, Gerald Voss, Carolyn A. Holland, Sathit Pichyangkul, Montip Gettayacamin, W. Ripley Ballou, Wolfgang W. Leitner
Publikováno v:
Vaccine. 24:4167-4178
RTS,S/AS02A, a recombinant Plasmodium falciparum vaccine based on the circumsporozoite protein (CSP) repeat and C-terminus regions, elicits strong humoral and Th1 cell-mediated immunity. In field studies, RTS,S/AS02A reduced malaria infection, clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9d381e8da62456e0dbc041367c81cf
https://doi.org/10.1016/j.vaccine.2006.02.041
https://doi.org/10.1016/j.vaccine.2006.02.041
Autor:
Jeffrey Kapali Lyon
Publikováno v:
Ka Ho'oilina/The Legacy. 5:38-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71222e62084dac9ee57e2a3d1e167694
https://doi.org/10.1353/kah.2006.0013
https://doi.org/10.1353/kah.2006.0013
Autor:
Josef Thalhamer, George C. Tsokos, Richard Weiss, David B. Winter, Evelina Angov, Elizabeth H. Duncan, Farhat Khan, Jeffrey A. Lyon, Jackie L. Williams, Wolfgang W. Leitner, Elke S. Bergmann-Leitner, Sandra Scheiblhofer, Defeng Chen
Publikováno v:
International Immunology. 17:245-255
The immunogenicity of recombinant protein or anti-viral DNA vaccines can be significantly improved by the addition of tandem copies of the complement fragment C3d. We sought to determine if the efficacy of a circumsporozoite protein (CSP)-based DNA v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb44626cc37f92cfc3439ab602e389a
https://doi.org/10.1093/intimm/dxh205
https://doi.org/10.1093/intimm/dxh205