Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Jeffrey A, Deiuliis"'
Autor:
Rengasamy Palanivel, Vinesh Vinayachandran, Shyam Biswal, Jeffrey A. Deiuliis, Roshan Padmanabhan, Bongsoo Park, Roopesh Singh Gangwar, Jared C. Durieux, Elaine Ann Ebreo Cara, Lopa Das, Graham Bevan, Zahi A. Fayad, Ahmed Tawakol, Mukesh K. Jain, Sujata Rao, Sanjay Rajagopalan
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101728- (2020)
Summary: Particulate matter ≤2.5μm (PM2.5) air pollution is a leading environmental risk factor contributing disproportionately to the global burden of non-communicable disease. We compared impact of chronic exposure to PM2.5 alone, or with light
Externí odkaz:
https://doaj.org/article/ee1b915295be4d6b92fb5c3734b768fc
Autor:
Jeffrey A Deiuliis, Rafay Syed, Dheeraj Duggineni, Jessica Rutsky, Palanivel Rengasamy, Jie Zhang, Kun Huang, Bradley Needleman, Dean Mikami, Kyle Perry, Jeffrey Hazey, Sanjay Rajagopalan
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165962 (2016)
Obesity in humans and mice is typified by an activated macrophage phenotype in the visceral adipose tissue (VAT) leading to increased macrophage-mediated inflammation. microRNAs (miRNAs) play an important role in regulating inflammatory pathways in m
Externí odkaz:
https://doaj.org/article/3503fdc4448847f4a1895ca4ceaac03b
Autor:
Jeffrey A. Deiuliis, Jinhu Yin, Sanjay Rajagopalan, Vinesh Vinayachandran, Youngshim Choi, Sadeer G. Al-Kindi, Roopesh Singh Gangwar, Rengasamy Palanivel, Mukesh K. Jain, Kasper D. Hansen, Bongsoo Park, Lopa M. Das, Shyam Biswal
Publikováno v:
J Clin Invest
Air pollution involving particulate matter smaller than 2.5 μm in size (PM(2.5)) is the world’s leading environmental risk factor contributing to mortality through cardiometabolic pathways. In this study, we modeled early life exposure using chow-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0abb9d8df541ded206396292fd0873
https://doi.org/10.1172/jci137315
https://doi.org/10.1172/jci137315
Autor:
Rengasamy Palanivel, Rama Natarajan, Lingxiao Zhang, Vishnu Amaram, Jeffrey A. Deiuliis, Kenneth Stapleton, Zhuo Chen, Linda Lanting, Marpadga A. Reddy, Sadhan Das, Amy Leung
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:914-928
Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular complications. This inflammatory state is caused by release of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d316219af70957369e6209b411253e8d
https://doi.org/10.1161/atvbaha.119.313359
https://doi.org/10.1161/atvbaha.119.313359
Autor:
Kenneth, Stapleton, Sadhan, Das, Marpadga A, Reddy, Amy, Leung, Vishnu, Amaram, Linda, Lanting, Zhuo, Chen, Lingxiao, Zhang, Rengasamy, Palanivel, Jeffrey A, Deiuliis, Rama, Natarajan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular compl
Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1031fb37f40b47b3ed7706340bd4a36
https://pubmed.ncbi.nlm.nih.gov/32078363
https://pubmed.ncbi.nlm.nih.gov/32078363
Publikováno v:
American Journal of Hypertension. 31:150-165
Noncoding RNAs (ncRNA) include a diverse range of functional RNA species—microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) being most studied in pathophysiology. Cardiovascular morbidity is associated with differential expression of myriad miRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa17ce7d6a69819888880af79031535
https://doi.org/10.1093/ajh/hpx197
https://doi.org/10.1093/ajh/hpx197
Publikováno v:
American Journal of Nephrology. 46:298-314
Background: The remarkable success of clinical trials in mineralocorticoid receptor (MR) inhibition in heart failure has driven research on the physiological and pathological role(s) of nonepithelial MR expression. MR is widely expressed in the cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fc208fc646c16c3877071a74299a0e
https://doi.org/10.1159/000480652
https://doi.org/10.1159/000480652
Autor:
Jeffrey A. Deiuliis, Rafay Syed
Obesity and associated comorbidities—insulin resistance, diabetes, dyslipidemia, and cardiovascular diseases—are rooted in myriad metabolic dysfunctions orchestrated in part by microRNAs. This chapter focuses on the most frequently reported micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::194325bf0773dc17209246afadde5aaf
https://doi.org/10.1039/9781788016421-00036
https://doi.org/10.1039/9781788016421-00036
Publikováno v:
Advanced Drug Delivery Reviews. 99:2-11
Clearance of apoptotic debris is a vital role of the innate immune system. Drawing upon principles of apoptotic clearance, convenient delivery vehicles including intrinsic anti-inflammatory characteristics and specificity to immune cells can be engin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a5f10c098826cb285cfc09bf60290b
https://doi.org/10.1016/j.addr.2016.01.009
https://doi.org/10.1016/j.addr.2016.01.009
Autor:
Jeffrey A. Deiuliis, Xiaoquan Rao, Sanjay Rajagopalan, Georgeta Mihai, Xiao Jian Sun, Simeon I. Taylor, Juliet Varghese, Chang Xia, Michael J. Quon, Jixin Zhong, Matthew B. Frieman, Carole Sztalryd
Publikováno v:
Diabetes Care
Studies including ours indicate that systemic inhibition of dipeptidyl peptidase 4 (DPP4), an ubiquitously expressed peptidase, by pharmaceutical inhibitors improved atherosclerosis (1,2). However, the role of immune cell–derived DPP4 is not well d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16b0e3d91726eb6175a57f596a86087
https://doi.org/10.2337/dc17-0672
https://doi.org/10.2337/dc17-0672