Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jeffrey T. Finer"'
Autor:
Kenneth W. Wood, Steve Weitman, Stephanie Roth, Paul Gonzales, John C. Chabala, Rebecca Turincio, Robert Moody, John Mak, Yan Lee, Alex Fritsch, Evan Lewis, Anne Crompton, Christophe Beraud, Jeffrey T. Finer, Roman Sakowicz
Several members of the kinesin family of microtubule motor proteins play essential roles in mitotic spindle function and are potential targets for the discovery of novel antimitotic cancer therapies. KSP, also known as HsEg5, is a kinesin that plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63dc20615231844dd86881f070830abd
https://doi.org/10.1158/0008-5472.c.6493848
https://doi.org/10.1158/0008-5472.c.6493848
Autor:
Kenneth W. Wood, Steve Weitman, Stephanie Roth, Paul Gonzales, John C. Chabala, Rebecca Turincio, Robert Moody, John Mak, Yan Lee, Alex Fritsch, Evan Lewis, Anne Crompton, Christophe Beraud, Jeffrey T. Finer, Roman Sakowicz
Supplementary Fig. 1 from Antitumor Activity of a Kinesin Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a7faec0e1a73fc24c5e3fb4f4e58d2
https://doi.org/10.1158/0008-5472.22363719
https://doi.org/10.1158/0008-5472.22363719
Autor:
Kenneth W. Wood, Steve Weitman, Stephanie Roth, Paul Gonzales, John C. Chabala, Rebecca Turincio, Robert Moody, John Mak, Yan Lee, Alex Fritsch, Evan Lewis, Anne Crompton, Christophe Beraud, Jeffrey T. Finer, Roman Sakowicz
Legends to Supplementary Figures from Antitumor Activity of a Kinesin Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6119ab3766a5b138206dc028e1f8d8e7
https://doi.org/10.1158/0008-5472.22363722
https://doi.org/10.1158/0008-5472.22363722
Autor:
Kenneth W. Wood, Steve Weitman, Stephanie Roth, Paul Gonzales, John C. Chabala, Rebecca Turincio, Robert Moody, John Mak, Yan Lee, Alex Fritsch, Evan Lewis, Anne Crompton, Christophe Beraud, Jeffrey T. Finer, Roman Sakowicz
Supplementary Fig. 3 from Antitumor Activity of a Kinesin Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdeb2bb4c283b679ad71a2fed8ed27d
https://doi.org/10.1158/0008-5472.22363713
https://doi.org/10.1158/0008-5472.22363713
Autor:
Kenneth W. Wood, Steve Weitman, Stephanie Roth, Paul Gonzales, John C. Chabala, Rebecca Turincio, Robert Moody, John Mak, Yan Lee, Alex Fritsch, Evan Lewis, Anne Crompton, Christophe Beraud, Jeffrey T. Finer, Roman Sakowicz
Supplementary Fig. 2 from Antitumor Activity of a Kinesin Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5370c2520da1d49f5e91efb3057db13e
https://doi.org/10.1158/0008-5472.22363716
https://doi.org/10.1158/0008-5472.22363716
Autor:
Katjuša Brejc, Jeffrey T. Finer, Maria Pokrovskii, David R. Cox, Daniel W. Pierce, Marc Garard, Ramesh Baliga, Congrong Niu, Todd Tochimoto, Kathleen A. Elias, Guillermo Godinez, Stephen F. Vatner, You Tang Shen, Roman Sakowicz, Bradley P. Morgan, Sandra H. Sueoka, Pu Ping Lu, Fady I. Malik, Tatsuo Katori, Alexander Muci, David Lenzi, David J. Morgans, Corey Valdez, Sheila Sylvester, Kenneth Lee, Xiangping Qian, Ion Suehiro, Erica Kraynack, Raja Kawas, David A. Kass, James J. Hartman, Hector P. Rodriguez, Robert L. Anderson, Wenyue Wang
Publikováno v:
Science. 331:1439-1443
Decreased cardiac contractility is a central feature of systolic heart failure. Existing drugs increase cardiac contractility indirectly through signaling cascades but are limited by their mechanism-related adverse effects. To avoid these limitations
Autor:
William F. Huffman, Ken A. Newlander, Amita M. Chaudhari, Shu-Yun Zhang, Michael L. Moore, Jeffrey T. Finer, Kevin J. Duffy, Antony N. Shaw, Melody Diamond, David Sutton, Robert A. Copeland, Michael N. Zimmerman, Chiu-Mei M Sung, Leo F. Faucette, Roman Sakowicz, Jeffrey R. Jackson, Lusong Luo, Kurt R. Auger, Kenneth W. Wood, Jeffrey D. Carson, Carla A. Donatelli, Cynthia A. Parrish, Erin D. Hugger, Steven D. Knight, Lance Ridgers, Nicholas D. Adams, Joelle Lorraine Burgess, Dashyant Dhanak
Publikováno v:
Journal of Medicinal Chemistry. 50:4939-4952
Kinesin spindle protein (KSP), an ATPase responsible for spindle pole separation during mitosis that is present only in proliferating cells, has become a novel and attractive anticancer target with potential for reduced side effects compared to curre
Publikováno v:
Proceedings of the National Academy of Sciences. 94:7927-7931
Observation of discrete, single-molecule binding events allows one to bypass assumptions required to infer single-molecule properties from studies of ensembles of molecules. Optically trapped beads and glass microneedles have been applied to detect s
Publikováno v:
Nature. 368:113-119
A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results from the interaction of a single myosin molecule with a single suspended actin filament. Discrete stepwise movements ave
Autor:
Gustave Bergnes, Pearl S. Huang, Jeffrey R. Jackson, Joel Greshock, Stephen Schauer, Yan Lee, David Sutton, Latesh Lad, Roland S. Annan, William K. Cornwell, Serge Lichtsteiner, Lisa D. Belmont, Chiu-Mei Sun, Roman Sakowicz, Michele Giardiniere, Neysa Nevins, Robert A. Copeland, Richard Wooster, David J. Morgans, Shu-Yun Zhang, Xiangping Qian, Jeffrey T. Finer, Steven D. Knight, Radhika Desai, Justin D. Vidal, Lusong Luo, Katjuša Brejc, Aidan G. Gilmartin, Dashyant Dhanak, Penelope Chua, Melody Diamond, Dean E. McNulty, Leo F. Faucette, Carmen García, Kenneth Wood
Centromere-associated protein-E (CENP-E) is a kinetochore-associated mitotic kinesin that is thought to function as the key receptor responsible for mitotic checkpoint signal transduction after interaction with spindle microtubules. We have identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2536ef86db2edbbcd78abd3682f5fa5
https://europepmc.org/articles/PMC2851928/
https://europepmc.org/articles/PMC2851928/