Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jeffrey R. Jackson"'
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Supplementary Tables 1-3 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63807349d8c5365b462bb33763b38e0
https://doi.org/10.1158/0008-5472.22378532.v1
https://doi.org/10.1158/0008-5472.22378532.v1
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Supplementary Figure Legends 1-4 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680e0f17f3ce8cc74f754d82f38def5e
https://doi.org/10.1158/0008-5472.22378538.v1
https://doi.org/10.1158/0008-5472.22378538.v1
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Supplementary Figures 1-4 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ad8ebae32a794098ee99c407b72872
https://doi.org/10.1158/0008-5472.22378535.v1
https://doi.org/10.1158/0008-5472.22378535.v1
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Additions to Supplement Table 3 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2382019a7bca7fdff5e1920fcfcedfa6
https://doi.org/10.1158/0008-5472.22378544.v1
https://doi.org/10.1158/0008-5472.22378544.v1
Autor:
Scott Jacobson, Jeffrey R. Jackson, Daniel Poon, Michelle Ko, Paul D. Kassner, Mikhail Zibinsky, Paul Leger, Heather Milestone, Deepika Kaveri, Anqi Ma, Thant Zaw, Lan Nguyen, Yamini M. Ohol, Tivitmahaisoon Parcharee, Chandru Ramana, Martin Brovarney, Delia Bradford, Cynthia Cho, Michael Sun, Lavanya Adusumilli, Jerick Sanchez, George E. Katibah, Omar Robles, Dan Nebalasca, Steve Wong, Blanca Gomez, Justy Gomez Guagua, Cyril Bucher, Rachel Ames, Mengshu Xu, David J. Wustrow, Anton Shakhmin, Andrew Ng, Dirk G. Brockstedt, Grant M. Shibuya, Molly Grandcolas
Publikováno v:
Cancer Research. 81:1646-1646
Hematopoietic progenitor kinase 1 (HPK1) is an intracellular protein kinase that negatively regulates T cell signaling and proliferation. Upon T cell receptor (TCR) activation, active HPK1 phosphorylates the adaptor protein SLP76 in the TCR complex,
Autor:
George E. Katibah, Anqi Ma, Lisa Marshall, Thant Zaw, Andrew Ng, Deepa Pookot, M. Teresa Ciudad, Buvana Ravishankar, Justy Gomez Guagua, Paul D. Kassner, Tracy L. McGaha, Raashi Sreenivasan, Jeffrey R. Jackson, James E. Talmadge, Anton Shakhmin, Mengshu Xu, Urvi Kolhatkar, Dirk G. Brockstedt, Scott Jacobson, Lavanya Adusumilli, Grant M. Shibuya, Paul Leger, Mikhail Zibinsky, Holly C. Britton, Gene Cutler, David J. Wustrow, Delia Bradford, Omar Robles, Steve Wong, Chandru Ramana
Publikováno v:
Cancer Research. 81:3153-3153
Recent advances in cancer metabolism suggest that targeting amino acid metabolism represents a promising strategy for the development of novel therapeutic agents. Tumor, stromal and myeloid-derived suppressor cells (MDSC) within the tumor microenviro
Autor:
Thomas S. King, Maria Bartanuszova, Linda Y Johnson, Arunabh Bhattacharya, Jeffrey R. Jackson, Jordan A. Tanner, Haley Nation, Beeran Jethwa, Nikita B. Ruparel, Alan Y. Sakaguchi, Ramaswamy Sharma
Publikováno v:
The FASEB Journal. 33
Autor:
Warren Hurlburt, Ann Greer, Tai W. Wong, Rolf-Peter Ryseck, John Cogswell, Craig Fairchild, Han Chang, Zhenhao Qi, Karen A. Reeves, Joan M. Carboni, Jeffrey R. Jackson, Stephen Hillerman, Friedrich Graf Finckenstein, Fei Huang, Dharmesh Patel
Publikováno v:
Molecular Cancer Therapeutics. 14:620-630
Insulin-like growth factor receptor 1 (IGF-1R)–targeting therapies are currently at an important crossroad given the low clinical response rates seen in unselected patients. Predictive biomarkers for patient selection are critical for improving cli
Autor:
Maureen R. Bleam, Christopher Moy, Sylvie Laquerre, Mark Richter, Jeffrey R. Jackson, Scott Powers, Wendy S. Halsey, Richard Wooster, Yan Degenhardt, Kurtis E. Bachman, Barbara L. Weber, Nancy Liu-Sullivan, Junping Jing, Ashley M. Hughes, Aidan G. Gilmartin, Joel Greshock, Xi-Ping Zhang
Publikováno v:
Molecular Cancer Therapeutics. 9:2079-2089
Polo-like kinases are a family of serine threonine kinases that are critical regulators of cell cycle progression and DNA damage response. Predictive biomarkers for the Plk1-selective inhibitor GSK461364A were identified by comparing the genomics and
Autor:
Maureen R. Bleam, Mark Richter, Lenore Madden, Mary P. Courtney, David Sutton, Ryan G. Kruger, Sylvie Laquerre, Melody Diamond, Symon G. Erskine, Aidan G. Gilmartin, Jeffrey R. Jackson, Gary K. Smith, Richard R. Gontarek, Daniel F. Hassler
Publikováno v:
Cancer Research. 69:6969-6977
Polo-like kinase 1 (Plk1) is a conserved serine/threonine kinase that plays an essential role in regulating the many processes involved in mitotic entry and progression. In humans, Plk1 is expressed primarily during late G2 and M phases and, in conju