Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Jeffrey F. Waring"'
Autor:
Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Determining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron
Externí odkaz:
https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7
Autor:
Justin E. Ideozu, Mengzhen Liu, Bridget M. Riley-Gillis, Sri R. Paladugu, Fedik Rahimov, Preethi Krishnan, Rakesh Tripathi, Patrick Dorr, Hara Levy, Ashvani Singh, Jeffrey F. Waring, Aparna Vasanthakumar
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Limited understanding of the diversity of variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene across ancestries hampers efforts to advance molecular diagnosis of cystic fibrosis (CF). The consequences p
Externí odkaz:
https://doaj.org/article/3b6ab30fd82f46199da1babff1f4bf31
Autor:
Lindsay R Stolzenburg, Sahar Esmaeeli, Ameya S Kulkarni, Erin Murphy, Taekyung Kwon, Christina Preiss, Lamiaa Bahnassawy, Joshua D Stender, Justine D Manos, Peter Reinhardt, Fedik Rahimov, Jeffrey F Waring, Cyril Y Ramathal
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291029 (2023)
Neurodegenerative diseases encompass a group of debilitating conditions resulting from progressive nerve cell death. Of these, Alzheimer's disease (AD) occurs most frequently, but is currently incurable and has limited treatment success. Late onset A
Externí odkaz:
https://doaj.org/article/395ae1654da24c70810025fdf7471ad2
Autor:
Aparna Vasanthakumar, Justin W Davis, Manal Abunimeh, Jonas Söderholm, Jiuhong Zha, Emily O Dumas, Daniel E Cohen, Jeffrey F Waring, Martin Lagging
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198296 (2018)
BACKGROUND:Genetic variants of inosine triphosphatase (ITPA) that confer reduced ITPase activity are associated with protection against ribavirin(RBV)-induced hemolytic anemia in peginterferon(IFN)/RBV-based treatment of hepatitis C virus (HCV). Pati
Externí odkaz:
https://doaj.org/article/23916246c20f4325ac0a6eac3286f175
Autor:
Mohan Liu, Jacob Degner, Justin Wade Davis, Kenneth B Idler, Ahmed Nader, Nael M Mostafa, Jeffrey F Waring
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195325 (2018)
Anti-drug antibody formation occurs with most biological agents across disease states, but the mechanism by which they are formed is unknown. The formation of anti-drug antibodies to adalimumab (AAA) may decrease its therapeutic effects in some patie
Externí odkaz:
https://doaj.org/article/54e61afa36b242ac93a2c3be0dc93e35
Autor:
Nizar Smaoui, Rahul Mehta, Tsing Cheng, Stephanie Manson Brown, Howard J. Jacob, Jeffrey F. Waring, Bridget Riley-Gillis, Mengzhen Liu, Ali Abbasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008df08e337be2ea32e1d4d11b83e45d
https://doi.org/10.26226/m.62fa009023ef91001a663bbd
https://doi.org/10.26226/m.62fa009023ef91001a663bbd
Autor:
Cyril Ramathal, David Masica, Peter Ansell, Bridget Riley-Gillis, Jacob Degner, Thanh Bui, Priya Narayanan, Josue Samayoa, Xin Huang, Robert F. Coleman, Jeffrey F. Waring
Publikováno v:
Cancer Research. 83:5426-5426
Discovery and validation of biomarkers derived from multi-dimensional clinico-genomic datasets have become critical in precision medicine and oncology drug development. The integration of multi-dimensional genomic and imaging datasets from patients i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10dbb2081e7f81e1e0aac8c98ff89320
https://doi.org/10.1158/1538-7445.am2023-5426
https://doi.org/10.1158/1538-7445.am2023-5426
Autor:
Bo-Hyun, Kim, Aparna, Vasanthakumar, Qingqin S, Li, Kelly N H, Nudelman, Shannon L, Risacher, Justin W, Davis, Kenneth, Idler, Jong-Min, Lee, Sang Won, Seo, Jeffrey F, Waring, Andrew J, Saykin, Kwangsik, Nho
Publikováno v:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 14
The acceleration of biological aging is a risk factor for Alzheimer's disease (AD). Here, we performed weighted gene co-expression network analysis (WGCNA) to identify modules and dysregulated genesinvolved in biological aging in AD.We performed WGCN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c54a00c0b61c185910475818bee6c4b
https://doi.org/10.1002/dad2.12354
https://doi.org/10.1002/dad2.12354
Autor:
Brenda Chyla, Matthew S. Davids, Stephan Stilgenbauer, Jeffrey F. Waring, Jeremy A. Ross, Eugen Tausch, Kenneth Robinson, Nabanita Mukherjee, Fengjiao Dunbar, Danjuma Quarless, Andrew J. Souers, Relja Popovic, Charles Lu, Joel D. Leverson, John Pesko, Scott E. Warder, Su Young Kim
Publikováno v:
American Journal of Hematology. 97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15528d0d9205c0108a09978f4a7bbd26
https://doi.org/10.1002/ajh.26411
https://doi.org/10.1002/ajh.26411
Autor:
Qingqin S. Li, Jeffrey F. Waring, Justin W. Davis, Kenneth B. Idler, Aparna Vasanthakumar, Andrew J. Saykin, Kwangsik Nho
Publikováno v:
Clinical Epigenetics
Background Identifying biomarkers associated with Alzheimer’s disease (AD) progression may enable patient enrichment and improve clinical trial designs. Epigenome-wide association studies have revealed correlations between DNA methylation at cytosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8b4f3df45499f5205b44843176e9c3
https://doi.org/10.1186/s13148-021-01179-2
https://doi.org/10.1186/s13148-021-01179-2