Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jeffrey, Sprouse"'
Autor:
Samantha T. Reyes, Robert M. J. Deacon, Scarlett G. Guo, Francisco J. Altimiras, Jessa B. Castillo, Berend van der Wildt, Aimara P. Morales, Jun Hyung Park, Daniel Klamer, Jarrett Rosenberg, Lindsay M. Oberman, Nell Rebowe, Jeffrey Sprouse, Christopher U. Missling, Christopher R. McCurdy, Patricia Cogram, Walter E. Kaufmann, Frederick T. Chin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Fragile X syndrome (FXS), a disorder of synaptic development and function, is the most prevalent genetic form of intellectual disability and autism spectrum disorder. FXS mouse models display clinically-relevant phenotypes, such as increased
Externí odkaz:
https://doaj.org/article/3fe726770d9a49e4a8f47d5b5a43daca
Autor:
Patricia Cogram, Robert M. J. Deacon, Daniel Klamer, Nell Rebowe, Jeffrey Sprouse, Samantha T. Reyes, Christopher U. Missling, Walter E. Kaufmann
Publikováno v:
American journal of medical genetics. Part AREFERENCES. 188(8)
Autor:
Berend van der Wildt, Daniel Klamer, Samantha T. Reyes, Jeffrey Sprouse, Robert M. J. Deacon, Nell Rebowe, Walter E. Kaufmann, Aimara P. Morales, Lindsay M. Oberman, Jarrett Rosenberg, Frederick T. Chin, Jun Hyung Park, Scarlett G. Guo, Francisco Altimiras, Christopher U. Missling, Jessa B. Castillo, Patricia Cogram, Christopher R. McCurdy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Fragile X syndrome (FXS), a disorder of synaptic development and function, is the most prevalent genetic form of intellectual disability and autism spectrum disorder. FXS mouse models display clinically-relevant phenotypes, such as increased anxiety
Autor:
Jessa B. Castillo, Berend van de Wildt, Nell Robowe, Scarlett G. Guo, Samantha T. Reyes, Jeffrey Sprouse, Jun Hyung Park, Christopher U. Missling, Aimara P. Morales, Frederick T. Chin
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Joost H.A. Folgering, Anne W. Schmidt, Jeffrey Sprouse, Anatoliy V. Gladkevich, Thomas I. F. H. Cremers, Johan A. den Boer, Marieke C. G. van der Hart, Ben H.C. Westerink, Fokko J. Bosker
Publikováno v:
Journal of Neurochemistry, 108(5), 1126-1135. Blackwell Publishing Ltd
Both microdialysis and electrophysiology were used to investigate whether another serotonin (5-HT) receptor subtype next to the 5-HT(1A) autoreceptor is involved in the acute effects of a selective serotonin reuptake inhibitor on 5-HT neuronal activi
Publikováno v:
Biological Psychiatry. 60:896-899
Background The documented ability of serotonin (5-HT) to directly modulate circadian rhythms prompted interest in a similar role for therapeutic agents that readily enhance 5-HT neurotransmission, namely the selective serotonin reuptake inhibitors (S
Publikováno v:
Journal of Biological Rhythms. 20:122-131
In vitro neuronal recordings in the SCN have clearly documented shifts in the peak of unit activity following the application of serotonergic agents, and yet selectivity issues with these very tools have limited progress in establishing the precise r
Publikováno v:
Neuropharmacology. 46:52-62
Neurons in the suprachiasmatic nucleus (SCN), the site of the endogenous biological clock in mammals, fire spontaneously, peaking in firing rate near ZT6 or at the midpoint of the light phase in a 12:12 light-dark cycle. In rat hypothalamic slices, t
Publikováno v:
Synapse. 54:111-118
Spontaneous firing rates of neurons in the suprachiasmatic nuclei (SCN) follow a consistent pattern, peaking near the midpoint of the light phase in a 12:12 light/dark schedule, and repeating this brief period of increased activity in subsequent circ
Publikováno v:
Neuropsychopharmacology. 21:622-631
Ziprasidone is a novel antipsychotic agent which binds with high affinity to 5-HT1A receptors (Ki = 3.4 nM), in addition to 5-HT1D, 5-HT2, and D2 sites. While it is an antagonist at these latter receptors, ziprasidone behaves as a 5-HT1A agonist in v