Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeffrey, Mosenson"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 31-41 (2017)
Muscle stem cells (MuSCs) hold great therapeutic potential for muscle genetic disorders, such as Duchenne muscular dystrophy (DMD). The CRISP/Cas9-based genome editing is a promising technology for correcting genetic alterations in mutant genes. In t
Externí odkaz:
https://doaj.org/article/e8ab65205786447ca990a73143c0fed3
Autor:
Zhonghui Zhang, Yuanfan Hong, Di Xiang, Pei Zhu, Elise Wu, Wen Li, Jeffrey Mosenson, Wen-Shu Wu
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 645-657 (2015)
miR-302/367 is the most abundant miRNA cluster in human embryonic stem cells (hESCs) and can promote somatic cell reprogramming. However, its role in hESCs remains poorly understood. Here, we studied functional roles of the endogenous miR-302/367 clu
Externí odkaz:
https://doaj.org/article/013dbb6971ff45629f45dd80125bac16
Autor:
Dinesh, Jaishankar, Cormac, Cosgrove, Prathyaya, Ramesh, James, Mahon, Rohan, Shivde, Emilia R, Dellacecca, Shiayin F, Yang, Jeffrey, Mosenson, José A, Guevara-Patiño, I Caroline, Le Poole
Publikováno v:
Cell Stress Chaperones
Developing immunosuppressive therapies for autoimmune diseases comes with a caveat that immunosuppression may promote the risk of developing other conditions or diseases. We have previously shown that biolistic delivery of an expression construct enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8a9b21e9d9e99f32073e12130f47a76
https://pubmed.ncbi.nlm.nih.gov/34542825
https://pubmed.ncbi.nlm.nih.gov/34542825
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 31-41 (2017)
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 31-41 (2017)
Muscle stem cells (MuSCs) hold great therapeutic potential for muscle genetic disorders, such as Duchenne muscular dystrophy (DMD). The CRISP/Cas9-based genome editing is a promising technology for correcting genetic alterations in mutant genes. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb95d4825fb5478faa2dea0b99f70ba
Autor:
Xin Wang, Wen Shu Wu, Yalu Zhou, Yuanfan Hong, Jeffrey Mosenson, Furen Wu, Pei Zhu, Gajendra S. Shekhawat
Publikováno v:
Stem Cells Translational Medicine
Muscle stem cells (MuSCs) exhibit robust myogenic potential in vivo, thus providing a promising curative treatment for muscle disorders. Ex vivo expansion of adult MuSCs is highly desired to achieve a therapeutic cell dose because of their scarcity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e056fbb5bf4866a01a2772ca0d41acc
https://doi.org/10.1002/sctm.16-0427
https://doi.org/10.1002/sctm.16-0427
Autor:
Yalu Zhou, Pei Zhu, Wen Shu Wu, Yue Sheng, Zhonghui Zhang, Di Xiang, Zhijian Qian, Yuanfan Hong, Jeffrey Mosenson
Publikováno v:
Leukemia
The stem cell factor (SCF)/c-Kit pathway has crucial roles in controlling hematopoietic stem cell (HSC) renewal. However, little is known about the intracellular regulation of the SCF/c-Kit pathway in HSCs. We report here that Slug, a zinc-finger tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb66fd3a6e3a7be882975cef58c5429a
https://doi.org/10.1038/leu.2016.201
https://doi.org/10.1038/leu.2016.201
Autor:
Pei Zhu, Jeffrey Mosenson, Wen Li, Elise Wu, Yuanfan Hong, Zhonghui Zhang, Di Xiang, Wen Shu Wu
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 4, Iss 4, Pp 645-657 (2015)
Stem Cell Reports, Vol 4, Iss 4, Pp 645-657 (2015)
Summary miR-302/367 is the most abundant miRNA cluster in human embryonic stem cells (hESCs) and can promote somatic cell reprogramming. However, its role in hESCs remains poorly understood. Here, we studied functional roles of the endogenous miR-302
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff31a10efd81d70f0d3ea7b0ede98e2
Publikováno v:
Experimental Dermatology. 22:566-569
Inducible heat-shock protein 70 (HSP70i) is a protein regulated by stress that protects cells from undergoing apoptosis. Such proteins are marvellously well conserved throughout evolution, which has placed them in the spotlight for helping to underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6def09272c1a8ec1cfc6af9eabd57e96
https://doi.org/10.1111/exd.12183
https://doi.org/10.1111/exd.12183
Autor:
Jeffrey Mosenson, Andrew Zloza, José A. Guevara-Patiño, Jared Klarquist, Allison J. Barfuss, I. Caroline Le Poole
Publikováno v:
Pigment Cell & Melanoma Research. 25:88-98
Summary HSP70i and other stress proteins have been used in anti-tumor vaccines. This begs the question whether HSP70i plays a unique role in immune activation. We vaccinated inducible HSP70i (Hsp70-1) knockout mice and wild-type animals with optimize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cea5185466e49a5d38b1cae09034815
https://doi.org/10.1111/j.1755-148x.2011.00916.x
https://doi.org/10.1111/j.1755-148x.2011.00916.x
Autor:
I. Caroline Le Poole, Michael I. Nishimura, Jonathan M. Eby, Jared Klarquist, B. Jack Longley, Jeffrey Mosenson, Elizabeth Garrett-Mayer, Shikhar Mehrotra, Shilpak Chatterjee, Victor H. Engelhard, Hee Kap Kang
Publikováno v:
Pigment cellmelanoma research. 27(6)
To generate a mouse model of spontaneous epidermal depigmentation, parental h3TA2 mice, expressing both a human-derived, tyrosinase-reactive T-cell receptor on T cells and the matching HLA-A2 transgene, were crossed to keratin 14-promoter driven, ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf10da212beadb7148360dfd2db23e3e
https://pubmed.ncbi.nlm.nih.gov/24935676
https://pubmed.ncbi.nlm.nih.gov/24935676