Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jeffrey, Hyams"'
Autor:
Sanam Soomro, Suresh Venkateswaran, Kamala Vanarsa, Marwa Kharboutli, Malavika Nidhi, Ramya Susarla, Ting Zhang, Prashanth Sasidharan, Kyung Hyun Lee, Joel Rosh, James Markowitz, Claudia Pedroza, Lee A. Denson, Jeffrey Hyams, Subra Kugathasan, Chandra Mohan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Stool biomarkers hold promise for monitoring disease activity and predicting clinical course in inflammatory bowel disease (IBD) as they originate from the inflamed tissue. Here the authors report an aptamer-based proteomic screen, and discover sever
Externí odkaz:
https://doaj.org/article/0e861c5d16cb448f88bdd0f9eeed0169
Autor:
Ohad, Atia, Zivia, Shavit-Brunschwig, Diane R, Mould, Ronen, Stein, Manar, Matar, Marina, Aloi, Oren, Ledder, Gili, Focht, Darja, Urlep, Jeffrey, Hyams, Efrat, Broide, Batia, Weiss, Jeremiah, Levine, Richard K, Russell, Dan, Turner
Publikováno v:
The Lancet Gastroenterology & Hepatology. 8:31-42
Scarce data are available on the use of vedolizumab in children with inflammatory bowel disease (IBD). We aimed to evaluate the safety, effectiveness, and dosing of vedolizumab to induce remission of IBD.VEDOKIDS was a paediatric, multicentre, prospe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb68d92ef0e90fe9e98f45222c4c858
https://doi.org/10.1016/s2468-1253(22)00307-7
https://doi.org/10.1016/s2468-1253(22)00307-7
Autor:
Peter C. Church, Jeffrey Hyams, Frank Ruemmele, Lissy de Ridder, Dan Turner, Anne M. Griffiths
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2018 (2018)
Background and Aims. Use of anti-TNF therapies varies internationally. As an initiative of the international Pediatric IBD Network (PIBDNet), we compared global pediatric IBD anti-TNF practice patterns. Methods. Physicians were surveyed about anti-TN
Externí odkaz:
https://doaj.org/article/c3d2a16181e14e7183c99349220322c8
Autor:
Jasbir Dhaliwal, Xiaoxuan Liu, Jim Reigle, Mihika Sharma, Oscar Lopez-Nunez, Tom Walters, Margaret Collins, Jeffrey Hyams, Iram Siddiqui, Lee Denson, Anil Jegga, Surya Prasath
Publikováno v:
Inflammatory Bowel Diseases. 29:S56-S57
BACKGROUND The majority of children with ulcerative colitis present with extensive colitis at diagnosis, but the response to therapy is heterogenous. Identifying the optimal window for biologic treatment and risk stratification of patients remains an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9c5072b793c5309137bdc8e079076d
https://doi.org/10.1093/ibd/izac247.109
https://doi.org/10.1093/ibd/izac247.109
Autor:
Brian G, Feagan, Stefan, Schreiber, Anita, Afzali, Florian, Rieder, Jeffrey, Hyams, Kanthi, Kollengode, Jared, Pearlman, Vladimir, Son, Cecilia, Marta, Douglas C, Wolf, Geert G, D'Haens
Publikováno v:
Contemporary clinical trials, 122:106958. Elsevier Inc.
Ozanimod, an oral sphingosine 1-phosphate receptor modulator currently approved for the treatment of moderately to severely active ulcerative colitis and relapsing multiple sclerosis, showed clinical, endoscopic, and histological benefit in the phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892a292e34889a787440b40c4be03a7c
https://doi.org/10.1016/j.cct.2022.106958
https://doi.org/10.1016/j.cct.2022.106958
Autor:
Gili Focht, Ruth Cytter-Kuint, Mary-Louise C. Greer, Li-Tal Pratt, Denise A. Castro, Peter C. Church, Thomas D. Walters, Jeffrey Hyams, Dan Navon, Javier Martin de Carpi, Frank Ruemmele, Richard K. Russell, Matan Gavish, Anne M. Griffiths, Dan Turner
Publikováno v:
Gastroenterology. 163(5)
Cross-sectional imaging is important in the assessment of transmural inflammation in Crohn's disease (CD). Small bowel involvement is often more extensive in pediatric CD, requiring a panentering measuring tool. We undertook to develop a magnetic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c80299c00b7fcffb5e5be194d57f35
https://pubmed.ncbi.nlm.nih.gov/36067818
https://pubmed.ncbi.nlm.nih.gov/36067818
Autor:
Ryan C, Ungaro, Liangyuan, Hu, Jiayi, Ji, Shikha, Nayar, Subra, Kugathasan, Lee A, Denson, Jeffrey, Hyams, Marla C, Dubinsky, Bruce E, Sands, Judy H, Cho
Publikováno v:
Aliment Pharmacol Ther
BACKGROUND: There is a need for improved risk stratification in Crohn’s disease. AIM: To identify novel blood protein biomarkers associated with future Crohn’s disease complications METHODS: We performed a case-cohort study utilising a paediatric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06ad180e74d7675df07956300c6caa9b
https://pubmed.ncbi.nlm.nih.gov/33131065
https://pubmed.ncbi.nlm.nih.gov/33131065
Autor:
Boyko Kabakchiev, Dan Turner, Jeffrey Hyams, David Mack, Neal Leleiko, Wallace Crandall, James Markowitz, Anthony R Otley, Wei Xu, Pingzhao Hu, Anne M Griffiths, Mark S Silverberg
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Microarray analysis of RNA expression allows gross examination of pathways operative in inflammation. We aimed to determine whether genes expressed in whole blood early following initiation of intravenous corticosteroid treatment can be associated wi
Externí odkaz:
https://doaj.org/article/a3d7b9aacfb34159b368c94cbd86a2c0
Autor:
Ruben Colman, Tomoyuki Mizuno, Jeffrey Hyams, Joshua Noe, Brendan Boyle, Lee Denson, Alexander Vinks, Phillip Minar
Publikováno v:
Inflammatory Bowel Diseases. 28:S100-S100
INTRODUCTION Use of vedolizumab in pediatric inflammatory bowel disease (IBD) often requires an interval intensification from standard dosing due to distinct pharmacokinetics (PK) in children. Adult population PK models found inclusion of albumin, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b8cb84b3b694b49e5efb959d10348f
https://doi.org/10.1093/ibd/izac015.162
https://doi.org/10.1093/ibd/izac015.162
Autor:
Kaitlin Whaley, Vivian Xiong, Rebekah Karns, Jeffrey Hyams, Subra Kugathasan, Brendan Boyle, Tom Walters, Judith Kelsen, Neal LeLeiko, Jason Shapiro, Amanda Waddell, Sejal Fox, Yael Haberman, Phillip Minar, Lee Denson, Geert D’Haens, Alexander Vinks, Michael Rosen
Publikováno v:
Inflammatory Bowel Diseases. 27:S55-S56
Background and Aims 25% of children hospitalized with acute severe ulcerative colitis (ASUC) rescued with infliximab (IFX) at labeled dosing undergo a colectomy prior to discharge. Our aim was to determine whether IFX pharmacokinetics (PK) are associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d8e58ecbea3bb4d518c9e747ce4b717
https://doi.org/10.1093/ibd/izaa347.132
https://doi.org/10.1093/ibd/izaa347.132