Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeffrey, Ackroyd"'
Autor:
Sunada Khadka, Kenisha Arthur, Yasaman Barekatain, Eliot Behr, Mykia Washington, Jeffrey Ackroyd, Kaitlyn Crowley, Pornpa Suriyamongkol, Yu-Hsi Lin, Cong-Dat Pham, Rafal Zielinski, Marissa Trujillo, James Galligan, Dimitra K. Georgiou, John Asara, Florian Muller
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background Reprogramming of metabolic pathways is crucial to satisfy the bioenergetic and biosynthetic demands and maintain the redox status of rapidly proliferating cancer cells. In tumors, the tricarboxylic acid (TCA) cycle generates biosy
Externí odkaz:
https://doaj.org/article/519bfa2cafdc47bf912b8bcc970dfde2
Autor:
Sunada Khadka, Yu-Hsi Lin, Jeffrey Ackroyd, Yi-An Chen, Yanghui Sheng, Wubin Qian, Sheng Guo, Yining Chen, Eliot Behr, Yasaman Barekatain, Md. Nasir Uddin, Kenisha Arthur, Victoria Yan, Wen-Hao Hsu, Edward Chang, Anton Poral, Theresa Tran, Surendra Chaurasia, Dimitra K. Georgiou, John M. Asara, Floris P. Barthel, Steve W. Millward, Ronald A. DePinho, Florian L. Muller
Tumor angiogenesis is a cancer hallmark, and its therapeutic inhibition has provided meaningful, albeit limited, clinical benefit. While anti-angiogenesis inhibitors deprive the tumor of oxygen and essential nutrients, cancer cells activate metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d46e48b0b718e73c869be6e50b0fc3a7
https://doi.org/10.1101/2023.05.07.539744
https://doi.org/10.1101/2023.05.07.539744
Autor:
Seth T. Gammon, Federica Pisaneschi, Madhavi L. Bandi, Melinda G. Smith, Yuting Sun, Yi Rao, Florian Muller, Franklin Wong, John De Groot, Jeffrey Ackroyd, Osama Mawlawi, Michael A. Davies, Y.N. Vashisht Gopal, M. Emilia Di Francesco, Joseph R. Marszalek, Mark Dewhirst, David Piwnica-Worms
Publikováno v:
Cells, Vol 8, Iss 12, p 1487 (2019)
Tumors lack a well-regulated vascular supply of O2 and often fail to balance O2 supply and demand. Net O2 tension within many tumors may not only depend on O2 delivery but also depend strongly on O2 demand. Thus, tumor O2 consumption rates may influe
Externí odkaz:
https://doaj.org/article/80e43aa655ad4afda9d992b8b65f87d1
Autor:
Prit Benny Malgulwar, Sharvari Dharmaiah, Benjamin Whitfield, Hannah Roberts, Jeffrey Ackroyd, Jason Huse
Publikováno v:
WFNOS 2022 Abstract Book.
Autor:
Yasaman Barekatain, Jeffrey Ackroyd, Victoria Yan, Sunada Khadka, Ko-Chien Chen, Raghu Kalluri, John de Groot, Jason Huse, Florian muller
Publikováno v:
Cancer Research. 82:2395-2395
Homozygous deletion of the CDK2NA locus frequently results in the co-deletion of methylthioadenosine phosphorylase (MTAP) in many fatal cancers such as glioblastoma multiform (GBM). In cell culture, cell lines with MTAP-deletions show elevations of i