Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Jeffrey, A Sparks"'
Autor:
Qiang Wang, Taehyeung Kim, Marta Martínez-Bonet, Vitor R. C. Aguiar, Sangwan Sim, Jing Cui, Jeffrey A. Sparks, Xiaoting Chen, Marc Todd, Brian Wauford, Miranda C. Marion, Carl D. Langefeld, Matthew T. Weirauch, Maria Gutierrez-Arcelus, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utiliz
Externí odkaz:
https://doaj.org/article/1e3df32c4843408cb3495d4e0d4bcf9e
Autor:
Jeffrey A. Sparks, Philippe Dieudé, Anna-Maria Hoffmann-Vold, Gerd R Burmester, Simon LF Walsh, Michael Kreuter, Christian Stock, Steven Sambevski, Margarida Alves, Paul Emery
Publikováno v:
BMC Rheumatology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Background Patients with rheumatoid arthritis (RA) are at risk of developing interstitial lung disease (ILD), which is associated with high mortality. Screening tools based on risk factors are needed to decide which patients with RA should b
Externí odkaz:
https://doaj.org/article/7f168e26c2354e6d9a2a6c55793ae5b1
Autor:
Sung Hae Chang, Seyoung Jung, Jeong Jun Chae, Jeong Yeon Kim, Seon Uk Kim, Ji Yong Choi, Hye-Jeong Han, Hyun Taek Kim, Hak-Jae Kim, Hyun Je Kim, Woong Yang Park, Jeffrey A. Sparks, Eun Young Lee, Jeong Seok Lee
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105339- (2024)
Summary: Background: Interstitial lung disease (ILD) poses a serious threat in patients with rheumatoid arthritis (RA). However, the impact of cornerstone drugs, including methotrexate (MTX) and TNF inhibitor, on RA-associated ILD (RA-ILD) remains co
Externí odkaz:
https://doaj.org/article/377aa910c3d24ae484c505fd18e89172
Autor:
Taehyeung Kim, Marta Martínez-Bonet, Qiang Wang, Nicolaj Hackert, Jeffrey A. Sparks, Yuriy Baglaenko, Byunghee Koh, Roxane Darbousset, Raquel Laza-Briviesca, Xiaoting Chen, Vitor R. C. Aguiar, Darren J. Chiu, Harm-Jan Westra, Maria Gutierrez-Arcelus, Matthew T. Weirauch, Soumya Raychaudhuri, Deepak A. Rao, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Fine-mapping and functional studies implicate rs117701653, a non-coding single nucleotide polymorphism in the CD28/CTLA4/ICOS locus, as a risk variant for rheumatoid arthritis and type 1 diabetes. Here, using DNA pulldown, mass spectrometry,
Externí odkaz:
https://doaj.org/article/89591f74d78449f789de95d34d7df2b8
Autor:
Elena K. Joerns, David Karp, Song Zhang, Jeffrey A. Sparks, Traci N. Adams, Una E. Makris, Chad A. Newton
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32118- (2024)
Abstract (144/150 words): Purpose: Cytokines can help predict prognosis in interstitial lung disease (ILD) and to differentiate between ILD subtypes. The objectives of our study were to evaluate association of baseline cytokine levels with time to IL
Externí odkaz:
https://doaj.org/article/ef6a819ffbe24160a05c7a16d47b41fb
Autor:
Gary M Hunninghake, Zachary S Wallace, Edwin K Silverman, George R Washko, Jeffrey A Sparks, Michael H Cho, Matthew Moll, Pierre-Antoine Juge, Elizabeth A Regan, Raul San Jose Estepar, Gregory L Kinney, Paul F Dellaripa, Samuel Y Ash, Keigo Hayashi, Tracy J Doyle, Xiaosong Wang, Misti L Paudel, Gregory C McDermott, Danielle Sansone-Poe, Kendra Young
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objective To compare longitudinal changes in spirometric measures between patients with rheumatoid arthritis (RA) and non-RA comparators.Methods We analysed longitudinal data from two prospective cohorts: the UK Biobank and COPDGene. Spirometry was c
Externí odkaz:
https://doaj.org/article/b97804e686c6402d8dfb8bd074530a64
Autor:
Walter C Willett, Karen H Costenbader, Medha Barbhaiya, Jeffrey A Sparks, Kazuki Yoshida, Chun-Han Lo, Susan Malspeis, Neha Khandpur, Sinara Laurini Rossato
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/d697a436fddc41dd9e0a2a38aca5f099
Autor:
Lucia Kwak, So Yeon Kim, Guru Sonpavde, Elad Sharon, Abdul Rafeh Naqash, Alessio Cortellini, Rana R McKay, Toni K Choueiri, Thomas Marron, Amin H Nassar, Jeffrey A Sparks, Kaushal Parikh, Frank Aboubakar Nana, Jenny Linnoila, Shruti Gupta, Nicole R LeBoeuf, Elio Adib, Ahmad Al-Hader, Edward El-Am, Dory Freeman, Ahmed Bilal Khalid, Marita Salame, Elias Bou Farhat, Arjun Ravishankar, Bachar Ahmad, David Kaldas, Andrea Malgeri, Ole-Petter R Hamnvik, Thomas Dilling, Elie Najem, Talal El Zarif, Serena Rahme, Caiwei Zhong, Tarek H Mouhieddine
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Patients with paraneoplastic syndromes (PNS) are excluded from clinical trials involving immune checkpoint inhibitors (ICIs) due to safety concerns. Moreover, real-world data on efficacy and safety is scarce.Methods In this retrospective s
Externí odkaz:
https://doaj.org/article/e3a36a44dc60429b90c5ae6bfb360660
Autor:
Ali Duarte-García, Kenneth J Warrington, Ashima Makol, Elena Myasoedova, Cynthia S Crowson, Jeffrey A Sparks, John M Davis, Vanessa L Kronzer, Andrew C Hanson, Robert Vassallo, Mattew J Koster, Alicia M Hinze, Kerry Wright
Publikováno v:
RMD Open, Vol 10, Iss 1 (2024)
Objectives To determine whether antecedent sinusitis is associated with incident rheumatic disease.Methods This population-based case–control study included all individuals meeting classification criteria for rheumatic diseases between 1995 and 201
Externí odkaz:
https://doaj.org/article/ef5f3a8ac6934e48bbfb7096bec7ae1b
Autor:
Lucia Kwak, So Yeon Kim, Elad Sharon, Abdul Rafeh Naqash, Alessio Cortellini, Toni K Choueiri, Rana Mckay, Jeffrey A Sparks, Kaushal Parikh, Frank Aboubakar Nana, Jenny Linnoila, Shruti Gupta, Nicole R LeBoeuf, Elio Adib, Amin Nassar, Talal El Zarif, Ahmed Bilal Khalid, Serena J Rahme, Marita Salame, Elias Bou Farhat, Edward El Am, Arjun Ravishankar, Bachar Ahmad, David Kaldas, Andrea Malgeri, Ole-Petter R Hamnvik, Thomas Dilling, Elie Najem, Guru P Sonpavde
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/df99a0c739d64783afe5458e630339d9