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pro vyhledávání: '"Jeffery W. Edenfield"'
Autor:
Julie C. Martin, Jeffrey Botbyl, Darlene Gibbon, Jeffery W. Edenfield, Diana Lindquist, Antoinette R. Tan, Mark N. Stein, Charles Gregory, Joseph J. Stephenson, A. Benjamin Suttle, Hiroomi Tada
Publikováno v:
Cancer chemotherapy and pharmacology. 71(6)
The metabolism of pazopanib is primarily mediated by CYP3A4. The solubility of pazopanib is pH-dependent, and an elevated gastric pH may decrease its bioavailability. This study evaluated the effect of a potent CYP3A4 inhibitor, ketoconazole, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25c1ad3cc813e820f872d73c5223938
https://pubmed.ncbi.nlm.nih.gov/23636448
https://pubmed.ncbi.nlm.nih.gov/23636448
