Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeffery S, Edmiston"'
Publikováno v:
Nicotine & Tobacco Research. 24:1047-1054
Introduction Long-term health effects of e-vapor products (EVPs) are not well-established. We compared biomarkers of exposure (BoE) to select harmful and potentially harmful constituents and biomarkers of potential harm (BoPH) in adult smokers who sw
Autor:
Nikola Pluym, Gerhard Scherer, Jeffery S. Edmiston, Xiaohong C. Jin, Mohamadi Sarkar, Max Scherer
Publikováno v:
Chemical research in toxicology. 35(4)
Publikováno v:
Internal and emergency medicine. 17(7)
Potential secondhand exposure of exhaled constituents from e-vapor product (EVP) use is a public health concern. We present a computational modeling method to predict air levels of exhaled constituents from EVP use. We measured select constituent lev
Publikováno v:
International Journal of Clinical Research & Trials. 5
Background: FDA is considering to establish a product standard to reduce nicotine in cigarettes to make them “minimally addictive or non addictive.” FDA has funded many clinical studies where smokers are switched to smoking low nicotine cigarette
Autor:
Donna C. Smith, Christopher R. E. Coggins, Ann M. Jerome, Jeffery S. Edmiston, Timothy B. Langston, Erica J. Sena, Michael J. Oldham
Publikováno v:
Inhalation Toxicology. 23:41-69
A total of 32 essential oils and resins were added individually to experimental cigarettes.A battery of tests was used to compare the toxicity of mainstream smoke from these experimental cigarettes. The lowest target inclusion level was 100 ppm and t
Autor:
Andrew R Joyce, Kellie J. Archer, Jeffery S. Edmiston, Barbara K. Zedler, Mariano J. Scian, E Lenn Murrelle
Publikováno v:
Biomarkers. 15:715-730
Background: Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease with associated systemic effects.Objective: To use gene expression microarrays in peripheral blood leukocytes of current and former cigarette smokers to identify
Autor:
Gaurav S J B, Rana, Timothy P, York, Jeffery S, Edmiston, Barbara K, Zedler, Joel G, Pounds, Joshua N, Adkins, Susan M, Varnum, Richard D, Smith, Zaigang, Liu, Guoya, Li, Bradley T, Webb, Edward L, Murrelle, Jason W, Flora
Publikováno v:
Analytical and Bioanalytical Chemistry. 397:1809-1819
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of morbidity and mortality in the United States and cigarette smoking is a primary determinant of the disease. COPD is characterized by chronic airflow limitation as measured by
Publikováno v:
Inhalation Toxicology. 21:234-243
In vitro systems are frequently used to study mechanisms of mainstream cigarette smoke (MS)-induced lung injury. Traditional methods of exposure involve the capture of MS particulate phase with filter pads or bubbling MS through phosphate buffered sa
Publikováno v:
Cancer Research. 65:4782-4788
It is well established that loss of a growth inhibitory response to transforming growth factor-β (TGF-β) is a common feature of epithelial cancers including esophageal cancer. However, the molecular basis for the abrogation of this key homeostatic
Autor:
Jeffery S. Edmiston, Deborah A. Lebman
Publikováno v:
Microbes and Infection. 1:1297-1304
Transforming growth factor-beta (TGF-beta) affects B cells at all stages in development. It appears to be involved in lymphopoiesis and is required for the development of plasma cells secreting all secondary isotypes. Its ability to inhibit prolifera