Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jeffery J. Pouliot"'
Autor:
John W. Seal, Dan Todd, Banka Anna L, Luz H. Carballo, Zhiping Xiong, Lisa L. Stroup, Amanda Mathis, Zhi Hong, Jeffery J. Pouliot, Pek Yoke Chong, Michael Youngman, Robert Hamatake, Daniel J. Price, Jing Fang, Katrina L. Creech, Andrew Spaltenstein, John G. Catalano, Christopher Don Roberts, J. Brad Shotwell, Andrew J. Peat, Vincent W.-F. Tai, John F. Miller, Sylvia Furst, Huichang Zhang
Publikováno v:
Journal of medicinal chemistry. 57(5)
We describe the preclinical development and in vivo efficacy of a novel chemical series that inhibits hepatitis C virus replication via direct interaction with the viral nonstructural protein 4B (NS4B). Significant potency improvements were realized
Autor:
Takita Felder, Amanda Galloway, Maria Marjorette O. Peña, H. Trent Spencer, Jeffery J. Pouliot, Michael C. Nivens
Publikováno v:
Cancer chemotherapy and pharmacology. 53(2)
Gene transfer of cDNA sequences that confer drug resistance can be used (1) to protect hematopoietic cells against the toxic effects of chemotherapy, (2) for in vivo enrichment of genetically engineered cells and (3) to protect cytotoxic T lymphocyte