Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jeffery Fairman"'
Autor:
Robin Ireland, Norma Olivares-Zavaleta, Jonathan M Warawa, Frank C Gherardini, Clayton Jarrett, B Joseph Hinnebusch, John T Belisle, Jeffery Fairman, Catharine M Bosio
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000921 (2010)
Protection against virulent pathogens that cause acute, fatal disease is often hampered by development of microbial resistance to traditional chemotherapeutics. Further, most successful pathogens possess an array of immune evasion strategies to avoid
Externí odkaz:
https://doaj.org/article/93aea17ff17e45c59cca2be8c7ad4968
Autor:
Terrence M. Tumpey, Xiangjie Sun, Jeffery Fairman, Jacqueline M. Katz, David B. Lewis, Feng Liu, Xiuhua Lu, Min Z. Levine
Publikováno v:
Virology. 492:197-203
Influenza A (H5N1) viruses continue to pose a public health threat. As inactivated H5N1 vaccines are poorly immunogenic, adjuvants are needed to improve the immunogenicity of H5N1 vaccine in humans. Here, we investigated the immunogenicity and cross-
Autor:
Jeffery Fairman, Michael B. McChesney, Christopher J. Miller, Sinthujan Jegaskanda, Stephen J. Kent, Linda Fritts, Shannon R. Matzinger, Timothy D. Carroll
Publikováno v:
The Journal of infectious diseases, vol 218, iss 6
BackgroundInfluenza A virus (IAV) vaccines offer little protection from mismatched viruses with antigenically distant hemagglutinin (HA) glycoproteins. We sought to determine if a cationic lipid/DNA complex (CLDC) adjuvant could induce heterosubtypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef30a316eda76a3cc94398cc09607aaa
https://escholarship.org/uc/item/7661v5rn
https://escholarship.org/uc/item/7661v5rn
Publikováno v:
BMC Cancer
Background Approximately 250 million people worldwide are chronically infected with hepatitis B virus (HBV) and more than half of the hepatocellular carcinoma (HCC) cases are attributed to this infection. As HCC has a high mortality rate, and current
Autor:
Peter A. Barry, Christopher J. Miller, Michael B. McChesney, Jeffery Fairman, Timothy D. Carroll, Shannon R. Matzinger
Publikováno v:
Journal of Infectious Diseases. 209:24-33
(See the editorial commentary by Kent on pages 4–5.) Seasonal influenza A virus infection is a highly contagious, acute respiratory tract disease of humans that causes substantial morbidity and mortality, particularly among those who are young, old
Autor:
Jeffery Fairman, Jacqueline M. Katz, Thomas P. Monath, Kathy Hancock, David B. Lewis, Libo Dong, Jenish R. Patel, Jessica A. Belser, John F. Warner, Xiuhua Lu, Feng Liu, David K. Hong
Publikováno v:
Vaccine. 30:254-264
+T-cell immunity a b s t r a c t The development of pre-pandemic influenza A H5N1 vaccines that confer both antigen-sparing and crossclade protection are a high priority given the limited worldwide capacity for influenza vaccine production, and the a
Publikováno v:
Antiviral Research. 90:227-230
Cationic lipid DNA complexes (CLDC), referred to here as JVRS-100, were evaluated as an adjuvant for hepatitis B surface antigen (HBsAg) for eliciting B and T cell responses in transgenic mice expressing hepatitis B virus (HBV). To confirm the immuno
Autor:
Crystal M. Botham, David K. Hong, Jeffery Fairman, Stella Chang, Thierry Giffon, David B. Lewis
Publikováno v:
Journal of Virology. 84:12691-12702
Influenza A virus is a negative-strand segmented RNA virus in which antigenically distinct viral subtypes are defined by the hemagglutinin (HA) and neuraminidase (NA) major viral surface proteins. An ideal inactivated vaccine for influenza A virus wo
Autor:
Bud C. Tennant, Stephan Menne, Paul J. Cote, Andrea L. George, Jeffery Fairman, Scott D. Butler, John L. Gerin
Publikováno v:
Journal of Medical Virology. 81:1760-1772
Complexes of cationic liposomes and non-coding DNA (CLDC) have shown promise as vaccine adjuvant. Using the woodchuck animal model of hepatitis B virus (HBV) infection, the immunogenic effects of CLDC were evaluated following vaccination with three d
Autor:
Hong Liang, Jan C. Liang, Lalitha Nagarajan, David Saltman, Lian Zhao, Rui yu Wang, Jeffery Fairman
Publikováno v:
Blood. 88:2259-2266
Acquired partial and complete deletions of chromosome 5 (5q-, -5) are common cytogenetic anomalies associated with myelodysplasia (MDS) and acute myeloid leukemia (AML). A critical region of consistent loss at 5q31.1 (in > 90% of cases) has led us an