Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jeffery D. Haines"'
Autor:
Deepali Mathur, Angela L. Riffo-Campos, Josefa Castillo, Jeffery D. Haines, Oscar G. Vidaurre, Fan Zhang, Francisco Coret-Ferrer, Patrizia Casaccia, Bonaventura Casanova, Gerardo Lopez-Rodas
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
In relapsing-remitting multiple sclerosis (RRMS) subtype, the patient’s brain itself is capable of repairing the damage, remyelinating the axon and recovering the neurological function. Cerebrospinal fluid (CSF) is in close proximity with brain par
Externí odkaz:
https://doaj.org/article/d682d7b9fd1f478cb59f3614db47aade
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145843 (2015)
We have previously shown that p38 mitogen-activated protein kinase (p38 MAPK) is important for oligodendrocyte (OLG) differentiation and myelination. However, the precise cellular mechanisms by which p38 regulates OLG differentiation remain largely u
Externí odkaz:
https://doaj.org/article/6ca7df20e7dc45d0b0b3767ebe82f7f8
Autor:
Panagiotis Douvaras, Tomasz Rusielewicz, Kwi Hye Kim, Jeffery D. Haines, Patrizia Casaccia, Valentina Fossati
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 4, p 614 (2016)
Pluripotent stem cells provide an invaluable tool for generating human, disease-relevant cells. Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system, characterized by myelin damage. Oligodendrocytes are the myelin
Externí odkaz:
https://doaj.org/article/c69dee5b2d2d445e8bf60a9fa10f5336
Autor:
Dilara McCauley, Patrizia Casaccia, Stephanie Albrecht, Belén de la Hera, Sharon Shacham, Oscar G. Vidaurre, Yuh Min Chook, Grahame J. Kidd, Tanja Kuhlmann, Konstantina Alexandropoulos, Olivier Herbin, Jeffery D. Haines, Ho Yee Joyce Fung, Gregory Moy, Qingxiang Sun
Publikováno v:
Nature Neuroscience. 18:511-520
Axonal damage has been associated with aberrant protein trafficking. We examined a newly characterized class of compounds that target nucleo-cytoplasmic shuttling by binding to the catalytic groove of the nuclear export protein XPO1 (also known as CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff9c052c6d59d36f24cc4a452d5bffd
https://doi.org/10.1038/nn.3953
https://doi.org/10.1038/nn.3953
Autor:
Patrizia Casaccia, Giulio Maria Pasinetti, Pavan Bhargava, Jimmy L. Huynh, Peter A. Calabresi, Corey A. McGraw, Ilana Katz Sand, Jeffery D. Haines, Merina Varghese, Fred D. Lublin, Aaron E. Miller, Norman J. Haughey, Oscar G. Vidaurre, Weijia Zhang, Elias S. Sotirchos, Veera Venkata Ratnam Bandaru, Fan Zhang, Gang Wu, Kadidia P. Adula, Matilde Inglese
Publikováno v:
Brain. 137:2271-2286
Axonal damage is a prominent cause of disability and yet its pathogenesis is incompletely understood. Using a xenogeneic system, here we define the bioenergetic changes induced in rat neurons by exposure to cerebrospinal fluid samples from patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdaee649d35910e74c0bbd9f15b8d76
https://doi.org/10.1093/brain/awu139
https://doi.org/10.1093/brain/awu139
Autor:
Jeffery D. Haines, Olivier Herbin
Publikováno v:
médecine/sciences. 31:604-606
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcdc9f43539bf25bdc5df3f4f7f544c3
https://doi.org/10.1051/medsci/20153106010
https://doi.org/10.1051/medsci/20153106010
Autor:
Jeffery D. Haines, Patrizia Casaccia, Panagiotis Douvaras, Tomasz Rusielewicz, Valentina Fossati, Kwi Hye Kim
Publikováno v:
International Journal of Molecular Sciences; Volume 17; Issue 4; Pages: 614
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 4, p 614 (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 4, p 614 (2016)
Pluripotent stem cells provide an invaluable tool for generating human, disease-relevant cells. Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system, characterized by myelin damage. Oligodendrocytes are the myelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d17c14c509e5447e50ccb02a9ba089e
Autor:
Juan Sandoval, Jia Liu, Jeffery D. Haines, Richard S. Nowakowski, Patrizia Casaccia, Oscar G. Vidaurre
Publikováno v:
European Journal of Neuroscience. 35:1879-1886
Therapeutic strategies are often based on two general principles: interference with the pathogenic process and repair of the damaged tissues. Recent studies, however, have suggested that several pathological conditions may result from the interplay b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6382809ebe2d754dd2ce997619ddedc
https://doi.org/10.1111/j.1460-9568.2012.08118.x
https://doi.org/10.1111/j.1460-9568.2012.08118.x
Autor:
Timothy J Schallert, Frederique Zindy, Mireya Marin-Husstege, José Manuel García-Verdugo, Kwi Hye Kim, Patrizia Casaccia, Jeffery D. Haines, Michael J. Spinetta, Jasbir Kaur, Maria Duran-Moreno, Sara Gil-Perotin, Martine F. Roussel
Publikováno v:
European Journal of Neuroscience. 34:1040-1052
The tumor suppressor protein p53 (Trp53) and the cell cycle inhibitor p27(Kip1) (Cdknb1) have both been implicated in regulating proliferation of adult subventricular zone (aSVZ) cells. We previously reported that genetic ablation of Trp53 (Trp53-/-)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35923fd03e660b1c37ba9e9d7074ceeb
https://doi.org/10.1111/j.1460-9568.2011.07836.x
https://doi.org/10.1111/j.1460-9568.2011.07836.x
Publikováno v:
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine. 78:231-243
Multiple sclerosis is a debilitating disease of the central nervous system that has been characteristically classified as an immune-mediated destruction of myelin, the protective coating on nerve fibers. Although the mechanisms responsible for the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a68d3e7b7ee0460f8e1ac828e3f676c
https://doi.org/10.1002/msj.20246
https://doi.org/10.1002/msj.20246