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pro vyhledávání: '"Jeffery Brender"'
Autor:
James Mitchell, Jeffery Brender, Ganesha Rai, Shun Kishimoto, Kazutoshi Yamamoto, David J. Maloney, Keita Saito, Leonard M. Neckers, Anastasia L. Sowers, Kristin Beebe, Murali Krishna Cherukuri, Nobu Oshima, Bryan T. Mott
Publikováno v:
Cancer Research. 77:2852-2852
[aim] Increased lactate production is a feature of many neoplasms, and Lactate Dehydrogenase A (LDH-A) plays a key role in conversion of pyruvate to lactate. LDHA inhibition, therefore, is considered to be a promising approach toward developing a new
Autor:
Nataliya Popovych, Kevin Hartman, Matthew George Chapman, Jeffery Brender, Ayyalusamy Ramamoorthy
Publikováno v:
Biophysical Journal. 100:539a
Proteins misfolded into insoluble, fibrillar aggregates known as amyloid are a pathological feature of many common and devastating diseases. Amyloid formation is typically a slow process that can be strongly affected by extrinsic factors, among the m