Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Jeffery A. Miller"'
Autor:
Christopher B. Chambers, Jeffrey Gross, Katherine Pratt, Xiang Guo, Colleen Byrnes, Y. Terry Lee, Donald Lavelle, Ann Dean, Jeffery L. Miller, Andrew Wilber
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 429-440 (2020)
Sickle cell disease (SCD) and β-thalassemia are caused by structural abnormality or inadequate production of adult hemoglobin (HbA, α2β2), respectively. Individuals with either disorder are asymptomatic before birth because fetal hemoglobin (HbF,
Externí odkaz:
https://doaj.org/article/0d5bb54e54684290a29829b79c64d624
Autor:
Jaira F. de Vasconcellos, Colleen Byrnes, Y. Terry Lee, Joshua M. Allwardt, Megha Kaushal, Antoinette Rabel, Jeffery L. Miller
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-13 (2017)
Abstract Background In humans, the heterochronic cascade composed of the RNA-binding protein LIN28 and its major target, the let-7 family of microRNAs (miRNAs), is highly regulated during human erythroid ontogeny. Additionally, down-regulation of the
Externí odkaz:
https://doaj.org/article/944361617b3849bd9fcb6aef45d94b5d
Autor:
Charlene Lam, Bryan E Anderson, Kassidy Shumaker, Jeffery J. Miller, Paul Leiphart, Melissa Butt
Publikováno v:
Archives of Dermatological Research. 314:71-76
Physician burnout and its association with the use of electronic health records (EHRs) is well known. The impact of scribes for academic dermatologists and their patients needs to be explored. As physician burnout increases, system-based solutions ar
Autor:
Jeffery T. Miller, Cameron F. Holder, Kazunori Fujisawa, Mauricio Terrones, Yifan Sun, Yuanxi Wang, Raymond E. Schaak, Jamie Y. C. Chen, Vincent H. Crespi
Publikováno v:
Nature Chemistry. 12:284-293
Functionalizing the surfaces of transition metal dichalcogenide (TMD) nanosheets with noble metals is important for electrically contacting them to devices, as well as improving their catalytic and sensing capabilities. Solution-phase deposition prov
Autor:
Jaira F de Vasconcellos, Y Terry Lee, Colleen Byrnes, Laxminath Tumburu, Antoinette Rabel, Jeffery L Miller
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166928 (2016)
Induction of fetal hemoglobin (HbF) has therapeutic importance for patients with beta-hemoglobin disorders. Previous studies showed that let-7 microRNAs (miRNAs) are highly regulated in erythroid cells during the fetal-to-adult developmental transiti
Externí odkaz:
https://doaj.org/article/6e85be65ef8c40d79322ed64756c05fa
Autor:
Megha Kaushal, Colleen Byrnes, Zarir Khademian, Natalie Duncan, Naomi L C Luban, Jeffery L Miller, Ross M Fasano, Emily Riehm Meier
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153244 (2016)
Sickle cell anemia (SCA) is an inherited hemolytic anemia with compensatory reticulocytosis. Recent studies have shown that increased levels of reticulocytosis during infancy are associated with increased hospitalizations for SCA sequelae as well as
Externí odkaz:
https://doaj.org/article/e1111f55b7e04fe5aa0a369b5f0e4298
Autor:
Y Terry Lee, Jaira F de Vasconcellos, Colleen Byrnes, Megha Kaushal, Antoinette Rabel, Laxminath Tumburu, Joshua M Allwardt, Jeffery L Miller
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144977 (2015)
Increasing fetal hemoglobin (HbF) levels in adult humans remains an active area in hematologic research. Here we explored erythroid-specific LIN28A expression for its effect in regulating gamma-globin gene expression and HbF levels in cultured adult
Externí odkaz:
https://doaj.org/article/1ed0f547493d4b89b40c0aed8de8c73d
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136672 (2015)
Hemoglobin switching is largely complete in humans by six months of age. Among infants with sickle cell anemia (HbSS, SCA), reticulocytosis begins early in life as fetal hemoglobin (HbF) is replaced by sickle hemoglobin (HbS). The objective of this s
Externí odkaz:
https://doaj.org/article/7dba86333b9f45f78d5f13eaa5219161
Autor:
Chenyang Li, J. M. Gregg, Jinsung Lee, Yidong Wan, Han Zong, Connie He, Liang Cao, Dong Su, Yuxuan Wang, Tim Mueller, Jeffery T. Miller, Xing Li, Chao Wang, Nicole J. Libretto
Publikováno v:
Journal of the American Chemical Society. 141:16635-16642
Alloying is an important strategy for the design of catalytic materials beyond pure metals. The conventional alloy catalysts however lack precise control over the local atomic structures of active ...
Autor:
Na Zhang, V. M. Yuen, Bi Lian Li, Jun Xiang Huang, Si Yuan Yang, Jeffery W. Miller, Huan Huan Zhang, Xing Rong Song
Publikováno v:
Journal of Autism and Developmental Disorders. 49:3798-3806
Children with autism often need sedation for diagnostic procedures and they are often difficult to sedate. This prospective randomized double-blind control trial evaluates the efficacy and safety using intranasal dexmedetomidine with and without bucc