Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jeffery A. McKie"'
Autor:
Meiqun Jiang, Stanley Didomenico, Ronald D. Snyder, Karen M. Alexander, Shripad S. Bhagwat, Guo Zhu Zheng, Carol T. Wismer, Haixia Yu, Andrew O. Stewart, Marilyn S. Diehl, Gregory A. Gfesser, Kennan C. Marsh, Erol K. Bayburt, Robin R. Frey, Mark A. Matulenko, Marlon D. Cowart, Jeffery A. McKie, Arthur Gomtsyan, Kathy L. Kohlhaas, Michael F. Jarvis, Elizabeth A. Kowaluk, Joseph P. Mikusa, Steve McGaraughty, Chih-Hung Lee
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:3705-3720
4-Amino-5,7-disubstituted pyridopyrimidines are potent, non-nucleoside inhibitors of adenosine kinase (AK). We recently identified a potent, orally efficacious analog, 4 containing a 7-pyridylmorpholine substituted ring system as the key structural e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95502834c737e63cdbb31651581d988
https://doi.org/10.1016/j.bmc.2005.03.023
https://doi.org/10.1016/j.bmc.2005.03.023
Autor:
Erol K. Bayburt, Jeffery A. McKie, Joe Mikusa, Shripad S. Bhagwat, Elizabeth A. Kowaluk, Chih-Hung Lee, Karen M. Alexander, Richard J. Perner, Michael F. Jarvis, Gu Yu-Gui, Kathy L. Kohlhaas, Carol T. Wismer
Publikováno v:
Journal of medicinal chemistry. 46(24)
The synthesis and structure-activity relationship of a series of 5,6,7-trisubstituted 4-aminopyrido[2,3-d]pyrimidines as novel nonnucleoside adenosine kinase inhibitors is described. A variety of alkyl, aryl, and heteroaryl substituents were found to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad6e28250e28b79764333e8423dbb91
https://pubmed.ncbi.nlm.nih.gov/14613327
https://pubmed.ncbi.nlm.nih.gov/14613327