Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Jeffery A, Hall"'
Autor:
Florian Pernin, Qiao-Ling Cui, Abdulshakour Mohammadnia, Milton G. F. Fernandes, Jeffery A. Hall, Myriam Srour, Roy W. R. Dudley, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Hannah E. Salapa, Michael C. Levin, G. R. Wayne Moore, Timothy E. Kennedy, Christine Vande Velde, Jack P. Antel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Oligodendrocyte (OL) injury and subsequent loss is a pathologic hallmark of multiple sclerosis (MS). Stress granules (SGs) are membrane-less organelles containing mRNAs stalled in translation and considered as participants of the cellular re
Externí odkaz:
https://doaj.org/article/7ecd4f332096485d86164c4aeb9e24fc
Autor:
Fatemeh Fadaie, Benoit Caldairou, Ravnoor S. Gill, Niels A. Foit, Jeffery A. Hall, Boris C. Bernhardt, Neda Bernasconi, Andrea Bernasconi
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103658- (2024)
Objective: In drug-resistant temporal lobe epilepsy (TLE), it is not well-established in how far surgery should target morphological anomalies to achieve seizure freedom. Here, we assessed interactions between structural brain compromise and surgery
Externí odkaz:
https://doaj.org/article/a6b75394285c46d8ada8a857a90c0450
Autor:
Moein Yaqubi, Adam M. R. Groh, Marie-France Dorion, Elia Afanasiev, Julia Xiao Xuan Luo, Hadi Hashemi, Sarthak Sinha, Nicholas W. Kieran, Manon Blain, Qiao-Ling Cui, Jeff Biernaskie, Myriam Srour, Roy Dudley, Jeffery A. Hall, Joshua A. Sonnen, Nathalie Arbour, Alexandre Prat, Jo Anne Stratton, Jack Antel, Luke M. Healy
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Microglia are tissue resident macrophages with a wide range of critically important functions in central nervous system development and homeostasis. Method In this study, we aimed to characterize the transcriptional landscape of e
Externí odkaz:
https://doaj.org/article/af75dc06fd684de888eae1e621a52263
Autor:
Maria Zimmermann, Luciano Minuzzi, Arturo Aliaga Aliaga, Marie-Christine Guiot, Jeffery A. Hall, Jean-Paul Soucy, Gassan Massarweh, Salah El Mestikawy, Pedro Rosa-Neto, Eliane Kobayashi
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Abnormalities in the expression of metabotropic glutamate receptor type 5 (mGluR5) have been observed in the hippocampus of patients with drug-resistant mesial Temporal Lobe Epilepsy (mTLE). Ex-vivo studies in mTLE hippocampal surgical specimens have
Externí odkaz:
https://doaj.org/article/f7eeb82c8de64b499db173d413f832be
Autor:
Milton Guilherme Forestieri Fernandes, Julia Xiao Xuan Luo, Qiao-Ling Cui, Kelly Perlman, Florian Pernin, Moein Yaqubi, Jeffery A. Hall, Roy Dudley, Myriam Srour, Charles P. Couturier, Kevin Petrecca, Catherine Larochelle, Luke M. Healy, Jo Anne Stratton, Timothy E. Kennedy, Jack P. Antel
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Milton Fernandes et al. combine single cell RNA-sequencing and functional assays to show that human oligodendrocytes exhibit an age-dependent resistance to apoptosis. Their findings have important implications for the pathology and treatment of myeli
Externí odkaz:
https://doaj.org/article/2f5ecb99de5f4c29b216220d02b72b5a
Autor:
Hui Ming Khoo, Nicolás vonEllenrieder, Natalja Zazubovits, Jeffery A. Hall, François Dubeau, Jean Gotman
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 6, Pp 1010-1023 (2019)
Abstract Objective A vast network involving the nodules and overlying cortices is believed to be responsible for the epileptogenicity in gray matter heterotopia with multiple nodules, which often associated with difficult‐to‐treat epilepsy. We so
Externí odkaz:
https://doaj.org/article/578c62a74f524afe8dd458e0f8ed4f93
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Neuronavigation using pre-operative imaging data for neurosurgical guidance is a ubiquitous tool for the planning and resection of oncologic brain disease. These systems are rendered unreliable when brain shift invalidates the patient-image registrat
Externí odkaz:
https://doaj.org/article/67aa92f8388442bc834f15ca23122bf1
Autor:
Jonathan M. DuBois, Sulantha Mathotaarachchi, Olivier G. Rousset, Viviane Sziklas, Jorge Sepulcre, Marie-Christine Guiot, Jeffery A. Hall, Gassan Massarweh, Jean-Paul Soucy, Pedro Rosa-Neto, Eliane Kobayashi
Publikováno v:
NeuroImage: Clinical, Vol 29, Iss , Pp 102552- (2021)
To determine the extent of metabotropic glutamate receptor type 5 (mGluR5) network abnormalities associated with focal cortical dysplasia (FCD), we performed graph theoretical analysis of [11C]ABP688 PET binding potentials (BPND), which allows for qu
Externí odkaz:
https://doaj.org/article/5eec106b713d46d3a7b0f4b1f28bb495
Autor:
Marie‐France Dorion, Moein Yaqubi, Hunter J. Murdoch, Jeffery A. Hall, Roy Dudley, Jack P. Antel, Thomas Martin Durcan, Luke Michael Healy
Publikováno v:
Glia. 71:1278-1293
Autor:
Casey Paquola, Jakob Seidlitz, Oualid Benkarim, Jessica Royer, Petr Klimes, Richard A I Bethlehem, Sara Larivière, Reinder Vos de Wael, Raul Rodríguez-Cruces, Jeffery A Hall, Birgit Frauscher, Jonathan Smallwood, Boris C Bernhardt
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000979 (2020)
The vast net of fibres within and underneath the cortex is optimised to support the convergence of different levels of brain organisation. Here, we propose a novel coordinate system of the human cortex based on an advanced model of its connectivity.
Externí odkaz:
https://doaj.org/article/58907f3b2d314ca0a324bb353b0c4067