Zobrazeno 1 - 10 of 89 pro vyhledávání: '"Jeff Yi Fu Chen"'
1
Akademický článek
Areca nut-induced metabolic reprogramming and M2 differentiation promote OPMD malignant transformation
Autor: Shyng-Shiou F. Yuan, Leong-Perng Chan, Hieu D. H. Nguyen, Chang-Wei Su, Yuk-Kwan Chen, Jeff Yi-Fu Chen, Shigetaka Shimodaira, Stephen Chu‐Sung Hu, Steven Lo, Yen-Yun Wang
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Betel quid and its major ingredient, areca nut, are recognized by IARC as major risk factors in oral cancer development. Areca nut extract (ANE) exposure has been linked to OPMD progression and malignant transformation to OSCC. Ho
Externí odkaz: https://doaj.org/article/4aa0750bbc754667b88858d4026a6076
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2
Akademický článek
The Role of Nonapoptotic Programmed Cell Death — Ferroptosis, Necroptosis, and Pyroptosis — in Pancreatic Ductal Adenocarcinoma Treatment
Autor: Sheng-Kai Hsu, Yi-Hsuan Chu, Wun-Jyun Syue, Hugo You-Hsien Lin, Wen-Tsan Chang, Jeff Yi-Fu Chen, Chang-Yi Wu, Chia-Hung Yen, Kai-Chun Cheng, Chien-Chih Chiu
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal cancer, with a dismal 5-year survival rate of less than 10%. It is estimated that approximately 80% of pancreatic ductal carcinoma (PDAC) patients are diagnosed at an advanced or metastatic s
Externí odkaz: https://doaj.org/article/9859978f96624386a78ee2b5124fb433
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3
Akademický článek
Endoglin Modulates TGFβR2 Induced VEGF and Proinflammatory Cytokine Axis Mediated Angiogenesis in Prolonged DEHP-Exposed Breast Cancer Cells
Autor: Mahendra Jadhao, Chun-Lin Chen, Wangta Liu, Dhanashri Deshmukh, Wei-Ting Liao, Jeff Yi-Fu Chen, Ritesh Urade, Eing-Mei Tsai, Sheng-Kai Hsu, Li-Fang Wang, Chien-Chih Chiu
Publikováno v: Biomedicines, Vol 10, Iss 2, p 417 (2022)
Angiogenesis is the process of vascular network development and plays a crucial role in cancer growth, progression, and metastasis. Phthalates are a class of environmental pollutants that have detrimental effects on human health and are reported to i
Externí odkaz: https://doaj.org/article/0b7296c7fad4445aad85c2a1cc352536
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6
Akademický článek
The Phenoxyphenol Compound diTFPP Mediates Exogenous C2-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells
Autor: Wen-Tsan Chang, Yung-Ding Bow, Yen-Chun Chen, Chia-Yang Li, Jeff Yi-Fu Chen, Yi-Ching Chu, Yen-Ni Teng, Ruei-Nian Li, Chien-Chih Chiu
Publikováno v: Antioxidants, Vol 10, Iss 3, p 394 (2021)
Hepatocellular carcinoma (HCC) is a severe disease that accounts for 80% of liver cancers. Chemotherapy is the primary therapeutic strategy for patients who cannot be treated with surgery or who have late-stage HCC. C2-ceramide is an effective reagen
Externí odkaz: https://doaj.org/article/1e36ccb46d4e4e8ba543f20e1d5b57cd
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7
Akademický článek
Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells
Autor: Chih-Chang Hung, Fu-An Li, Shih-Shin Liang, Ling-Feng Wang, I-Ling Lin, Chien-Chih Chiu, Chiu-Hsien Lee, Jeff Yi-Fu Chen
Publikováno v: Molecules, Vol 25, Iss 17, p 3815 (2020)
Prolonged treatment with cisplatin (CDDP) frequently develops chemoresistance. We have previously shown that p22phox, an endoplasmic reticulum (ER) membrane protein, confers CDDP resistance by blocking CDDP nuclear entry in oral squamous cell carcino
Externí odkaz: https://doaj.org/article/f74be978d21f462b86e1e8e617f917d0
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8
Akademický článek
Vitamin D decreases the secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 in fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyposis
Autor: Ling-Feng Wang, Chih-Feng Tai, Chen-Yu Chien, Feng-Yu Chiang, Jeff Yi-Fu Chen
Publikováno v: Kaohsiung Journal of Medical Sciences, Vol 31, Iss 5, Pp 235-240 (2015)
Vitamin D and its derivatives have modulatory effects in immunological and inflammatory responses. Such properties suggest that they might have an impact on chronic inflammatory airway diseases, including nasal polyposis. The aim of this study was to
Externí odkaz: https://doaj.org/article/9a3d02f1ebfd4e85a49c10b9800c0e94
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9
Akademický článek
Vitamin D decreases the secretion of eotaxin and RANTES in nasal polyp fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyps
Autor: Ling-Feng Wang, Chen-Yu Chien, Chih-Feng Tai, Feng-Yu Chiang, Jeff Yi-Fu Chen
Publikováno v: Kaohsiung Journal of Medical Sciences, Vol 31, Iss 2, Pp 63-69 (2015)
Eosinophils are important inflammatory cells involved in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). Vitamin D and its derivatives, in addition to their classic role as regulators of electrolytes homeostasis, have modulator
Externí odkaz: https://doaj.org/article/c98885ea2a8240bc80e17b60a3680b4b
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10
Akademický článek
13-Acetoxysarcocrassolide Induces Apoptosis on Human Gastric Carcinoma Cells Through Mitochondria-Related Apoptotic Pathways: p38/JNK Activation and PI3K/AKT Suppression
Autor: Ching-Chyuan Su, Jeff Yi-Fu Chen, Zhong-Hao Din, Jui-Hsin Su, Zih-Yan Yang, Yi-Jen Chen, Robert Y.L. Wang, Yu-Jen Wu
Publikováno v: Marine Drugs, Vol 12, Iss 10, Pp 5295-5315 (2014)
13-acetoxysarcocrassolide (13-AC), an active compound isolated from cultured Formosa soft coral Sarcophyton crassocaule, was found to possess anti-proliferative and apoptosis-inducing activities against AGS (human gastric adenocarcinoma cells) gastri
Externí odkaz: https://doaj.org/article/278cda5a957c4e48b567d0a61ac11585
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