Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jeff W. Paslay"'
Autor:
G. Sitta Sittampalam, Robert P. Hertzberg, William P. Janzen, Dragan A. Cirovic, Ricardo Macarron, David J. Burns, Tina Garyantes, Martyn Banks, Darren V. S. Green, Jeff W. Paslay, Dejan Bojanic, Ulrich Schopfer
Publikováno v:
Nature Reviews Drug Discovery. 10:188-195
High-throughput screening (HTS) has been postulated in several quarters to be a contributory factor to the decline in productivity in the pharmaceutical industry. Moreover, it has been blamed for stifling the creativity that drug discovery demands. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0f5fd05d9f368f1dc535c4360ed993
https://doi.org/10.1038/nrd3368
https://doi.org/10.1038/nrd3368
Autor:
Ricardo, Macarron, Martyn N, Banks, Dejan, Bojanic, David J, Burns, Dragan A, Cirovic, Tina, Garyantes, Darren V S, Green, Robert P, Hertzberg, William P, Janzen, Jeff W, Paslay, Ulrich, Schopfer, G Sitta, Sittampalam
Publikováno v:
Nature reviews. Drug discovery. 10(3)
High-throughput screening (HTS) has been postulated in several quarters to be a contributory factor to the decline in productivity in the pharmaceutical industry. Moreover, it has been blamed for stifling the creativity that drug discovery demands. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c3fccc1e84f7da4f88b80412cdddcb4
https://pubmed.ncbi.nlm.nih.gov/21358738
https://pubmed.ncbi.nlm.nih.gov/21358738
Autor:
Edward J. Kaftan, Kristi Fan, Scott Christian Mayer, Gregory J. Tawa, Dmitry V. Vasilyev, John W. Ellingboe, Dominick Mobilio, Jeff W. Paslay, Mark R. Bowlby, John Dunlop, David J. Diller, John A. Butera, Belew Mekonnen
Publikováno v:
Assay and drug development technologies. 8(4)
Ion channels have provided a diverse set of therapeutic targets across all areas of the pharmaceutical industry. Many companies are pursuing this unique class of targets for areas of unmet medical need such as neuropathic and inflammatory pains. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0c2ab8237a5f23ca51ba468375175e
https://pubmed.ncbi.nlm.nih.gov/20470241
https://pubmed.ncbi.nlm.nih.gov/20470241
Publikováno v:
Assay and drug development technologies. 8(3)
Transient receptor potential (TRP) channels have been found to play important roles in cellular physiology and hold promise as therapeutic targets. These channels activate in response to a variety of chemical or physical stimuli and conduct non-selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c651966057b49543aafd1c0dd1977472
https://pubmed.ncbi.nlm.nih.gov/20085483
https://pubmed.ncbi.nlm.nih.gov/20085483
Autor:
James K. Hennan, Richard K. Harrison, Belew Mekonnen, Larocque James Paul, Jeff Tillett, Manoj Samuel, Jeff W. Paslay, Veronica Soloveva, Kun Liu
Publikováno v:
Journal of biomolecular screening. 15(2)
Voltage-gated K(+) channels are potential drug targets for an increasing number of disease indications. Searching for compounds that modulate K(+) channel activities by high-throughput screening (HTS) is becoming a standard approach in the drug disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cecb0addb21e2bfbe49ffe8ed2ffea22
https://pubmed.ncbi.nlm.nih.gov/20044579
https://pubmed.ncbi.nlm.nih.gov/20044579
Publikováno v:
Topics in Medicinal Chemistry ISBN: 9783642010743
High throughput screening (HTS) has become the cornerstone of lead identification for small molecules in drug discovery during the last quarter century. The evolution of the sciences and technologies that have evolved as the foundation of modern HTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc85f25c6dcb7551d0c3e9d6f1abd9f1
https://doi.org/10.1007/7355_2009_6
https://doi.org/10.1007/7355_2009_6
Autor:
Jeff W. Paslay
Publikováno v:
SLAS Discovery. 13:835
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb9850da7880b492e0758ddcb04742b8
https://doi.org/10.1177/1087057108325310
https://doi.org/10.1177/1087057108325310
Publikováno v:
Assay & Drug Development Technologies; Jun2010, Vol. 8 Issue 3, p380-388, 9p