Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Jeff W. Lichtman"'
Autor:
Xiaomeng Han, Xiaotang Lu, Peter H. Li, Shuohong Wang, Richard Schalek, Yaron Meirovitch, Zudi Lin, Jason Adhinarta, Karl D. Murray, Leah M. MacNiven, Daniel R. Berger, Yuelong Wu, Tao Fang, Elif Sevde Meral, Shadnan Asraf, Hidde Ploegh, Hanspeter Pfister, Donglai Wei, Viren Jain, James S. Trimmer, Jeff W. Lichtman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Mapping neuronal networks is a central focus in neuroscience. While volume electron microscopy (vEM) can reveal the fine structure of neuronal networks (connectomics), it does not provide molecular information to identify cell types or funct
Externí odkaz:
https://doaj.org/article/af6d34c529a5478a859e10bc1f1a99bb
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
IntroductionMacular Telangiectasia type 2 (MacTel), is an uncommon form of late-onset, slowly-progressive macular degeneration. Associated with regional Müller glial cell loss in the retina and the amino acid serine synthesized by Müller cells, the
Externí odkaz:
https://doaj.org/article/e1774c291eeb42c183cf54483b710e31
Autor:
Elisa C. Pavarino, Emma Yang, Nagaraju Dhanyasi, Mona D. Wang, Flavie Bidel, Xiaotang Lu, Fuming Yang, Core Francisco Park, Mukesh Bangalore Renuka, Brandon Drescher, Aravinthan D. T. Samuel, Binyamin Hochner, Paul S. Katz, Mei Zhen, Jeff W. Lichtman, Yaron Meirovitch
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Connectomics is fundamental in propelling our understanding of the nervous system's organization, unearthing cells and wiring diagrams reconstructed from volume electron microscopy (EM) datasets. Such reconstructions, on the one hand, have benefited
Externí odkaz:
https://doaj.org/article/1571f27f677d4726bb49bd827fbb0a66
Autor:
Morgan Sanchez, Dymon Moore, Erik C. Johnson, Brock Wester, Jeff W. Lichtman, William Gray-Roncal
Publikováno v:
Frontiers in Neuroinformatics, Vol 16 (2022)
Neuroscientists can leverage technological advances to image neural tissue across a range of different scales, potentially forming the basis for the next generation of brain atlases and circuit reconstructions at submicron resolution, using Electron
Externí odkaz:
https://doaj.org/article/d64c809606304b4a841d5cd7f25281a8
Autor:
Lamiae Abdeladim, Katherine S. Matho, Solène Clavreul, Pierre Mahou, Jean-Marc Sintes, Xavier Solinas, Ignacio Arganda-Carreras, Stephen G. Turney, Jeff W. Lichtman, Anatole Chessel, Alexis-Pierre Bemelmans, Karine Loulier, Willy Supatto, Jean Livet, Emmanuel Beaurepaire
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Multicolour images are difficult to acquire with large-scale microscopy approaches. Here the authors present a microtome-assisted microscope capable of trichromatic two-photon excitation and label-free nonlinear modalities based on wavelength mixing,
Externí odkaz:
https://doaj.org/article/936f22a7c3dd47068d7ddbe4fade0e58
Autor:
Josh L. Morgan, Jeff W. Lichtman
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue
Externí odkaz:
https://doaj.org/article/ea712e437c5348a3af21d80e4096b343
Autor:
Shinsuke Shibata, Taro Iseda, Takayuki Mitsuhashi, Atsushi Oka, Tomoko Shindo, Nobuko Moritoki, Toshihiro Nagai, Shinya Otsubo, Takashi Inoue, Erika Sasaki, Chihiro Akazawa, Takao Takahashi, Richard Schalek, Jeff W. Lichtman, Hideyuki Okano
Publikováno v:
Frontiers in Neural Circuits, Vol 13 (2019)
Recent improvements in correlative light and electron microscopy (CLEM) technology have led to dramatic improvements in the ability to observe tissues and cells. Fluorescence labeling has been used to visualize the localization of molecules of intere
Externí odkaz:
https://doaj.org/article/cd0a3e8020234ccf85fa395879cdf45e
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
Recent developments in serial-section electron microscopy allow the efficient generation of very large image data sets but analyzing such data poses challenges for software tools. Here we introduce Volume Annotation and Segmentation Tool (VAST), a fr
Externí odkaz:
https://doaj.org/article/3f30750c7ef94e29a8c22f58ad82993d
Autor:
Lamiae Abdeladim, Katherine S. Matho, Solène Clavreul, Pierre Mahou, Jean-Marc Sintes, Xavier Solinas, Ignacio Arganda-Carreras, Stephen G. Turney, Jeff W. Lichtman, Anatole Chessel, Alexis-Pierre Bemelmans, Karine Loulier, Willy Supatto, Jean Livet, Emmanuel Beaurepaire
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Affiliation 4 incorrectly read ‘University of the Basque Country (Ikerbasque), University of the Basque Country and Donostia International Physics Center, San Sebastian 20018, Spain.’ Also, the affiliations of Ignacio Arganda-Carreras with ‘IKE
Externí odkaz:
https://doaj.org/article/14c92ea4f09f4501a3fc3bf6cc95a03b
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 11-11 (2018)
OBJECTIVES/SPECIFIC AIMS: Müller cells, radial glial cells of the retina, are the principal repository of xanthophyll pigment (lutein, zeaxanthin, meso-zeaxanthin), which are modifiable by diet and visible clinically by autofluorescence imaging. To
Externí odkaz:
https://doaj.org/article/29128bb478ed4e83997f673ae67500a6