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pro vyhledávání: '"Jeff Trimmer"'
Autor:
Derek M Erion, Amanda Lapworth, Paul A Amor, Guoyun Bai, Nicholas B Vera, Ronald W Clark, Qingyun Yan, Yimin Zhu, Trenton T Ross, Julie Purkal, Matthew Gorgoglione, Guodong Zhang, Vinicius Bonato, Levenia Baker, Nicole Barucci, Theresa D'Aquila, Alan Robertson, Robert J Aiello, Jiangli Yan, Jeff Trimmer, Timothy P Rolph, Jeffrey A Pfefferkorn
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97139 (2014)
Hyperglycemia resulting from type 2 diabetes mellitus (T2DM) is the main cause of diabetic complications such as retinopathy and neuropathy. A reduction in hyperglycemia has been shown to prevent these associated complications supporting the importan
Externí odkaz:
https://doaj.org/article/646e9e91d00f42f6a75e558c5e50e7cf
Autor:
Anuraag R. Kansal, Jeff Trimmer
Publikováno v:
Systems biology. 152(4)
The challenge of accurately predicting human clinical outcome based on preclinical data has led to a high failure rate of compounds in human clinical trials. A series of methods are described by which biosimulation can address these challenges and gu