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Abstract 587: ACLX-002, a novel CD123-targeted universal CAR-T cell therapy for relapsed or refractory acute myeloid leukemia that can be activated and silenced in vivo with soluble protein adapters in a dose dependent manner

Autor: Justin P. Edwards, Liubov Zaritskaya, Jeff Swers, Sinnie Ng, Jenny Mu, Alexandra Witter, Laurene Cheung, Samantha McCullough, David LaFleur, David Hilbert, David Tice

Publikováno v: Cancer Research. 82:587-587

Genetically engineered T cells have demonstrated great promise in the treatment of hematologic malignancies including Acute Lymphocytic Leukemia, Non-Hodgkin’s lymphoma and Multiple Myeloma. However, those successes are often associated with seriou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e805cc171c6b161a9fba44efe6ba7886
https://doi.org/10.1158/1538-7445.am2022-587

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