Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeff Sparks"'
Publikováno v:
Virginia Water Environment Federation Annual Education Seminar; Richmond, VA; May 4-5, 2022.
Autor:
Andrew P. Ferretti, Majed Matar, Jeff Sparks, Sabrina Ramelli, William T. Gerthoffer, Lydia L. Sandy, Jason G. Fewell, Jared M. McLendon, Brian S. Comer, Robert A. Barrington
Publikováno v:
Molecular Therapy. Nucleic Acids
To address the problem of poor asthma control due to drug resistance, an antisense oligonucleotide complementary to mmu-miR-145a-5p (antimiR-145) was tested in a house dust mite mouse model of mild/moderate asthma. miR-145 was targeted to reduce infl
Publikováno v:
Forest Ecology and Management. 396:91-101
In 2011, the most destructive wildfire in Texas history (Bastrop County Complex Fire, BCCF) burned 34,000 acres including most of Bastrop State Park. We used dendrochronological analysis of vegetation paired with documentary information to reconstruc
Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension
Autor:
Masahiko Oka, Jeff Sparks, Sachindra R. Joshi, Jason G. Fewell, William T. Gerthoffer, Ivan F. McMurtry, Jared M. McLendon, Majed Matar, Kohtaro Abe
Publikováno v:
Journal of Controlled Release. 210:67-75
Therapies that exploit RNA interference (RNAi) hold great potential for improving disease outcomes. However, there are several challenges that limit the application of RNAi therapeutics. One of the most important challenges is effective delivery of o
Publikováno v:
Polymers for Biomedicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461721d7662d3e7161ff2c13a742841f
https://doi.org/10.1002/9781118967904.ch9
https://doi.org/10.1002/9781118967904.ch9
Autor:
Casey Pence, Majed Matar, David Ulkoski, Leslie Wilkinson, Jason G. Fewell, Elaine Brunhoeber, Kirby Wallace, Diane McClure, Gregory Slobodkin, Jennifer Rice, Richard Congo, Angela Rea-Ramsey, Kevin Polach, Jeff Sparks, Khursheed Anwer
Publikováno v:
Journal of Controlled Release. 158:269-276
Exploitation of the RNA interference (RNAi) pathway offers the promise of new and effective therapies for a wide variety of diseases. Clinical development of new drugs based on this platform technology is still limited, however, by a lack of safe and
Publikováno v:
Rangeland Ecology & Management. 64:419-423
Empirical data generated from fire scars are a foundation for understanding fire regimes, designing land-management objectives, and addressing long-term land-use and climate-change effects. We derived precise dates of historic fires from fire-scar in
Autor:
Jeff Sparks, Carmen Scholz
Publikováno v:
Biomacromolecules. 9:2091-2096
Poly(beta-hydroxyalkanoates) (PHAs) are biodegradable polyesters produced by a wide range of bacteria. The structures of these polymers may be tuned by controlling the carbon source composition in the feed stock, but the range of functional groups ac
Autor:
Jeff Sparks, Diane McClure, Khursheed Anwer, Jennifer Rice, Kelley Smith, Stefanie Greenleaf, Elaine Brunhoeber, Majed Matar, Jason G. Fewell
Publikováno v:
Cancer Research. 76:2078-2078
Despite recent improvements in treatment options for ovarian cancer patients, notably, the approval of using bevacizumab in combination with chemotherapies including pegylated liposomal doxorubicin (PLD), this disease is still the most deadly of all
Autor:
Anke Geick, Kerstin Jahn-Hofmann, Monika Krampert, Jennifer Rice, Andrea Schuster, Khursheed Anwer, Richard Congo, Hans-Peter Vornlocher, Gregory Slobodkin, Jason G. Fewell, Diane McClure, Matthias John, Jeff Sparks, Angela Rea-Ramsey, Kevin Polach, Majed Matar, Elaine Brunhoeber
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 20(1)
We have designed a series of versatile lipopolyamines which are amenable to chemical modification for in vivo delivery of small interfering RNA (siRNA). This report focuses on one such lipopolyamine (Staramine), its functionalized derivatives and the