Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jeff S. Jasper"'
Autor:
Kimberly J. Cocce, Jeff S. Jasper, Taylor K. Desautels, Logan Everett, Suzanne Wardell, Thomas Westerling, Robert Baldi, Tricia M. Wright, Kendall Tavares, Alex Yllanes, Yeeun Bae, Jeremy T. Blitzer, Craig Logsdon, Daniel P. Rakiec, David A. Ruddy, Tiancong Jiang, Gloria Broadwater, Terry Hyslop, Allison Hall, Muriel Laine, Linda Phung, Geoffrey L. Greene, Lesley-Ann Martin, Sunil Pancholi, Mitch Dowsett, Simone Detre, Jeffrey R. Marks, Gregory E. Crawford, Myles Brown, John D. Norris, Ching-yi Chang, Donald P. McDonnell
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 889-903.e10 (2019)
Summary: Notwithstanding the positive clinical impact of endocrine therapies in estrogen receptor-alpha (ERα)-positive breast cancer, de novo and acquired resistance limits the therapeutic lifespan of existing drugs. Taking the position that resista
Externí odkaz:
https://doaj.org/article/c0b467352d604bac96892990f6f1dd91
Autor:
Sunghee Park, Ching-Yi Chang, Rachid Safi, Xiaojing Liu, Robert Baldi, Jeff S. Jasper, Grace R. Anderson, Tingyu Liu, Jeffrey C. Rathmell, Mark W. Dewhirst, Kris C. Wood, Jason W. Locasale, Donald P. McDonnell
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 323-335 (2016)
Imaging studies in animals and in humans have indicated that the oxygenation and nutritional status of solid tumors is dynamic. Furthermore, the extremely low level of glucose within tumors, while reflecting its rapid uptake and metabolism, also sugg
Externí odkaz:
https://doaj.org/article/8b3b7d737fc9404299f8033052271ea4
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Supplementary Materials and Methods, Figure Legends from Delineation of a FOXA1/ERα/AGR2 Regulatory Loop That Is Dysregulated in Endocrine Therapy–Resistant Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499dc20dc5ba31885862bd7fb221878f
https://doi.org/10.1158/1541-7786.22510780
https://doi.org/10.1158/1541-7786.22510780
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Supplementary Figure 4: ERα knockdown in MCF7 and TamR cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6f36ec6617054454dc99abd26eed8a
https://doi.org/10.1158/1541-7786.22510795.v1
https://doi.org/10.1158/1541-7786.22510795.v1
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Supplementary Figure 1: AGR2 expression in an in vivo model of tamoxifen resistance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ec03286a8cc0105ef2f4c33ce314c2
https://doi.org/10.1158/1541-7786.22510804
https://doi.org/10.1158/1541-7786.22510804
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Supplementary Figure 7: FOXA1 regulates AGR2 expression in MCF7 GPS ER cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5576465d036b063fbd3089a4fc5c3678
https://doi.org/10.1158/1541-7786.22510783.v1
https://doi.org/10.1158/1541-7786.22510783.v1
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Supplementary Figure 3: Rescue of AGR2 specific proliferation with conditional AGR2 media.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3178521dad33f847cd6a88fe0ef9e1dc
https://doi.org/10.1158/1541-7786.22510798.v1
https://doi.org/10.1158/1541-7786.22510798.v1
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Supplementary Figure 2: AGR2 apoptosis analysis in tamoxifen sensitive MCF7 and tamoxifen resistant TamR cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0e7dfd3141e1699ff2ad532a86b496
https://doi.org/10.1158/1541-7786.22510801
https://doi.org/10.1158/1541-7786.22510801
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Supplementary Figure 6: ChIP Analysis of AGR2 promoter.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1d0943f268258c33e25d89239b4d1c
https://doi.org/10.1158/1541-7786.22510786.v1
https://doi.org/10.1158/1541-7786.22510786.v1
Autor:
Donald P. McDonnell, Erik R. Nelson, Rachid Safi, James P. Stice, Jeff S. Jasper, Suzanne E. Wardell, Tricia M. Wright
Tamoxifen, a selective estrogen receptor (ER) modulator (SERM), remains a frontline clinical therapy for patients with ERα-positive breast cancer. However, the relatively rapid development of resistance to this drug in the metastatic setting remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2163230f55871268f8425e0d759a88b6
https://doi.org/10.1158/1541-7786.c.6539737
https://doi.org/10.1158/1541-7786.c.6539737