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pro vyhledávání: '"Jeff P. Varnerin"'
Autor:
Michael J. Forrest, Matthew J. Wyvratt, Lex H.T. Van der Ploeg, Kajal Patel, Michael H. Fisher, Ann E. Weber, Jiafang He, Anthony Mastracchio, Emma R. Parmee, Michael R. Tota, Euan Macintyre, Scott D. Edmondson, Xinchun Tong, Naphtali A. O'Connor, Joseph M. Metzger, Jeff P. Varnerin, Christine C. Chung, Scott Hofsess
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:3983-3987
Aryldihydropyridazinones and aryldimethylpyrazolones with 2-benzyl vinylogous amide substituents have been identified as potent PDE3B subtype selective inhibitors. Dihydropyridazinone 8a (PDE3B IC 50 =0.19 nM, 3A IC 50 =1.3 nM) was selected for in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a716655952e30da51f523a1480673a13
https://doi.org/10.1016/j.bmcl.2003.08.056
https://doi.org/10.1016/j.bmcl.2003.08.056
