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pro vyhledávání: '"Jeff M. Kucharski"'
Autor:
Yi Liu, Pingda Ren, Anjali Babbar, Sarah J. Firdaus, Jeffrey H. Chen, Tess Ely, Jun Feng, Jeff M. Kucharski, Yuching Chen, Linda V. Kessler, Ulf Peters, Rasmus Hansen, Lian-Sheng Li, Matthew R. Janes, Matthew P. Patricelli
Supplementary Table 1. Biochemical and Cell engagement SAR. Supplementary Table 2. Data collection and refinement statistics (Molecular replacement). Supplementary Table 3. Selectivity of ARS-853 across KRAS isoforms and GTP vs. GDP states. Supplemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb4c1da5f413c618429e4a216ba9b29
https://doi.org/10.1158/2159-8290.22531619
https://doi.org/10.1158/2159-8290.22531619
Autor:
Katti Jessen, Pingda Ren, Jean S. Oak, Michael B. Martin, Lomon So, Jeff M. Kucharski, Linda V. Kessler, Qiao Han Ke, Arun Manmadhan, Lian-Sheng Li, David A. Fruman, Sung Su Yea, Yi Liu, Matthew R. Janes, Mengrou Lu, Christian Rommel
Publikováno v:
The Journal of biological chemistry. 288(8)
Class IA phosphoinositide 3-kinase (PI3K) is essential for clonal expansion, differentiation, and effector function of B and T lymphocytes. The p110δ catalytic isoform of PI3K is highly expressed in lymphocytes and plays a prominent role in B and T