Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jeff L. Sigman"'
Autor:
Darla K. Liles, Gary G. Koch, Arthur P. Bode, Timothy C. Nichols, Shu Li, Thomas R. Griggs, Jeff L. Sigman, Gregory J. Dehmer, David A. Tate
Publikováno v:
The American Journal of Cardiology. 80:871-877
Three markers of platelet activation (platelet-derived microparticles, fibrinogen binding and expression of P-selectin) were assessed by flow cytometry during diagnostic coronary angiography and therapeutic coronary interventions. In 24 patients unde
Autor:
J. Scott Smith, Ting-Kai Li, Kenneth M. Brinkhous, Christel Boudignon-Proudhon, Marjorie S. Read, Jeff L. Sigman, Lawrence Lumeng, Leslie V. Parise, Scott V. Smith, Robert L. Reddick
Publikováno v:
Journal of Laboratory and Clinical Medicine. 128:601-611
A new hereditary thrombopathy has been identified in a closed colony of Wistar rats. A simple and reproducible cuticle bleeding time test was developed as a rapid screening procedure for the bleeding diathesis. Affected animals exhibit markedly prolo
Autor:
Marjorie S. Read, Robert G Schaub, Gregg Timony, James C. Keith, Scott D. Leppanen, Kenneth M. Brinkhous, Jeff L. Sigman, Bonita J. Rup, Paula F. Stewart, Kyle P. McCarthy, Pamela D. Garzone
Publikováno v:
Blood. 88:2603-2610
Recombinant human factor IX (rFIX) has been expressed in transduced cultured cell systems since 1985. Because there has been limited in vivo testing of rFIX in hemophilia B subjects, this study was undertaken using the severe hemophilia B canines of
Autor:
Ludovic Drouet, Jeff L. Sigman, Elisabeth M. Cramer, G. Pignaud, Jacqueline Roussi, Marcel Vaiman, Jean-Marc Massé, Michel Bonneau
Publikováno v:
British Journal of Haematology. 90:661-668
In order to study the relationship between plasma and platelet von Willebrand factor (vWF), we used an experimental model of crossed bone marrow transplantation (BMT) between SLA immunocompatible normal and homozygous von Willebrand (vWD) pigs. A nor
Autor:
Dwight A. Bellinger, Timothy C. Nichols, Robert L. Reddick, Keir E. Davis, Gary G. Koch, Thomas R. Griggs, Kenneth M. Brinkhous, Scott V. Smith, Jeff L. Sigman, Marjorie S. Read
Publikováno v:
Blood. 81:2644-2651
We have studied the roles of von Willebrand factor (vWF) and factor VIII in arterial thrombosis in four canine phenotypes: normal (n = 6), hemophilia A (n = 11), von Willebrand disease (vWD) (n = 9), and hemophilia A/vWD (n = 1). vWF activity was det
von Willebrand factor does not influence atherogenesis in arteries subjected to altered shear stress
Autor:
Thomas R. Griggs, Marjorie S. Read, Gary G. Koch, Dwight A. Bellinger, Robert L. Reddick, Timothy A. Johnson, Timothy C. Nichols, Tracey du Laney, Jeff L. Sigman, Geoffrey Erickson
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 18(2)
Abstract —The role of von Willebrand factor (vWF) in arterial neointimal formation that develops in arteries with altered shear stress was investigated using normal, heterozygous, and homozygous von Willebrand disease pigs (ie, vWD, or lacking vWF)