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pro vyhledávání: '"Jeff L Oostwegel"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 65:449-457
NMDA antagonists and dopamine (DA) agonists produce neuropathological and/or behavioral changes in rats that may model specific abnormalities in schizophrenia patients. In adult rats, NMDA antagonists and DA agonists disrupt sensorimotor gating-measu
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 23(5)
Both dopamine (DA) agonists and NMDA antagonists produce prepulse inhibition (PPI) deficits in rats that model PPI deficits in schizophrenia patients. While DA agonist effects on PPI are reversed by acute treatment with either “typical” high-pote
Publikováno v:
Behavioural pharmacology. 9(5-6)
Animal models in behavioral pharmacology can be evaluated based on their face, predictive and construct validity. A further level of validity may be achieved if a model is reproduced precisely across species - from laboratory animal to human - using
Publikováno v:
Biological Psychiatry. 47:S36
Autor:
Eric Griez, Alessandro Colasanti, Abdul Dandachi, Eva L. van Donkelaar, Jeff L. Oostwegel, Erik den Boer, Annerieke Horlings, Gabriel Esquivel, Koen Schruers
Publikováno v:
Psychopharmacology, 215(4), 739-748. Springer
Psychopharmacology
Psychopharmacology
Rationale It has been reported that in panic disorder (PD), tryptophan depletion enhances the vulnerability to experimentally induced panic, while the administration of serotonin precursors blunts the response to challenges. Objectives Using a high-d