Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeff Gillespie"'
Autor:
Annie Barsalou, Normand Beaulieu, Marja Dubay, Naomy Bernstein, Jeff Gillespie, Marie-France Robert, Jubrail Rahil, Isabelle Dupont, Ian Chute, Sylvain Lefebvre, Marie-Claude Granger, Hannah Nguyen, Oscar Mario Saavedra, James Wang, Jeffrey M. Besterman, Serge Gravel, Amal Wahhab, Lijie Zhan, Arkadii Vaisburg, Roussen Pascal, Carole Beaulieu, Zhiyun Jin, Franck Raeppel, Robert Deziel, David B. Llewellyn, A. Robert MacLeod, Stephen William Claridge
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2793-2798
A series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases is described. The compounds demonstrated potency with IC50 values in the low nanomolar range in vitro while the lead compound also showed in vivo activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c793d69f791b3bd653b579bbb81a8c8
https://doi.org/10.1016/j.bmcl.2008.04.009
https://doi.org/10.1016/j.bmcl.2008.04.009
Autor:
Giliane Bouchain, James Wang, Jeffrey M. Besterman, Marielle Fournel, Pu Theresa Yan, J Yuk, Oscar Moradei, Frédéric Gaudette, Marie-Claude Trachy-Bourget, Jubrail Rahil, Marie-France Robert, Aihua Lu, Zuomei Li, Naomy Bernstein, Stephane Raeppel, Zhiyun Jin, Isabelle Paquin, Jeff Gillespie, Daniel Delorme, Sylvie Frechette, Soon Hyung Woo, Arkadii Vaisburg, Nancy Z. Zhou, Silvana Leit, A. Robert MacLeod
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6729-6733
A variety of N-(2-amino-phenyl)-4-(heteroarylmethyl)-benzamides were designed and synthesized. These compounds were shown to inhibit recombinant human HDAC1 with IC(50) values in the sub-micromolar range. In human cancer cells growing in culture thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b6fada81d115e2a32d6d5463db4da9
https://doi.org/10.1016/j.bmcl.2007.10.050
https://doi.org/10.1016/j.bmcl.2007.10.050
Autor:
Jeff Gillespie
Publikováno v:
Music Theory Online. 15
[1] It is a tremendous honor to be here as part of this panel of distinguished colleagues. Never in my wildest dreams did I ever think I would be in a position to share such personal information in a national venue such as MTO. To be included here is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c96d7a1acf0cc772ed70de279841ff57
https://doi.org/10.30535/mto.15.3.8
https://doi.org/10.30535/mto.15.3.8
Autor:
Marielle Fournel, Pu T. Yan, Jeffrey M. Besterman, Ann Kalita, Zhiyun Jin, Jubrail Rahil, Marie-Claude Trachy-Bourget, Isabelle Paquin, Frédéric Gaudette, Stephane Raeppel, Silvana Leit, Giliane Bouchain, Jeff Gillespie, Zuomei Li, Daniel Delorme, Arkadii Vaisburg, A. Robert MacLeod, Naomy Bernstein, Sylvie Frechette, Aihua Lu, Nancy Z. Zhou, Oscar Moradei, James Wang
Publikováno v:
Journal of medicinal chemistry. 51(14)
The design, synthesis, and biological evaluation of N-(2-aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide 8 (MGCD0103) is described. Compound 8 is an isotype-selective small molecule histone deacetylase (HDAC) inhibitor that select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28adc0f0867119cc50f5d14d42ae6957
https://pubmed.ncbi.nlm.nih.gov/18570366
https://pubmed.ncbi.nlm.nih.gov/18570366
Autor:
Nancy Zhou, Oscar Moradei, Stephane Raeppel, Silvana Leit, Sylvie Frechette, Frederic Gaudette, Isabelle Paquin, Naomy Bernstein, Giliane Bouchain, Zhiyun Jin, Jeff Gillespie, James Wang, Marielle Fournel, Pu T. Yan, Marie-Claude Trachy-Bourget, Ann Kalita, Aihua Lu, Jubrail Rahil, A. Robert MacLeod, Zuomei Li
Publikováno v:
Journal of Medicinal Chemistry; Jun2008, Vol. 51 Issue 14, p4072-4075, 4p