Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jeff Francis"'
Autor:
Chris T. Williamson, Rowan Miller, Helen N. Pemberton, Samuel E. Jones, James Campbell, Asha Konde, Nicholas Badham, Rumana Rafiq, Rachel Brough, Aditi Gulati, Colm J. Ryan, Jeff Francis, Peter B. Vermulen, Andrew R. Reynolds, Philip M. Reaper, John R. Pollard, Alan Ashworth, Christopher J. Lord
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Mutations in the BAF SWI/SNF complex subunits are frequent in cancers but selective therapeutic approaches are not available yet. Here, the authors demonstrate that defects ofARID1Aand other subunits sensitizes cancer cells to the DNA checkpoint kina
Externí odkaz:
https://doaj.org/article/e641244f3cf24d9e87d1e6540b5b48bf
We present the results of a multi-season field evaluation of a low-cost optical particle counting sensor (Purple Air PA-II) that reports mass concentration of particulate matter with diameter less than 2.5 microns (PM2.5), and is part of a relatively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1c3612ef613c1f49a607d405fe1c9e
Autor:
Amanda Swain, Jeff Francis
Publikováno v:
Cold Spring Harb Perspect Med
The prostate is a male exocrine gland that secretes components of the seminal fluid. In men, prostate tumors are one of the most prevalent cancers. Studies on the development of the prostate have given a better understanding of the processes and gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4242a5b01b88a8e263e2e8dd702049d7
https://europepmc.org/articles/PMC6027935/
https://europepmc.org/articles/PMC6027935/
Autor:
Alec Paschalis, Antje Neeb, Amanda Swain, Mateus Crespo, Lorna Pope, Adam Sharp, Jun Luo, Gunther Boysen, Daniel Nava Rodrigues, Yezi Zhu, Maryou B. Lambros, Johann S. de Bono, Jon Welti, Ines Figueiredo, Jian Ning, David Dolling, Stephen R. Plymate, Bissan Al-Lazikani, Eleanor Knight, Veronica Gil, Jeff Francis, Wei Yuan
Publikováno v:
Cancer Research. 78:A067-A067
Despite robust responses to androgen deprivation therapy and AR targeting therapies (including abiraterone and enzalutamide), nearly all cases of advanced prostate cancer progress to lethal mCRPC and develop therapeutic resistance. This progression i
Autor:
Jonathan Welti, Amanda Swain, Johann S. de Bono, Ines Figueiredo, Jeff Francis, Antje Neeb, Daniel Nava Rodrigues, Wei Yuan, Eleanor Knight, Veronica Gil, Gunther Boysen, Jian Ning, Adam Sharp
Publikováno v:
Cancer Research. 77:1515-1515
Persistent androgen receptor (AR) signaling is key to the development and progression of metastatic castration resistant prostate cancer (mCRPC). This is in part due to expression of constitutively active AR splice variants like AR variant 7 (ARV7),