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pro vyhledávání: '"Jeff Fergusson"'
Autor:
Zhi Liu, Dai-Shi Su, Sanjay Kumar, Kimberly Roland, Lin Xiaojuan, Rick Keenan, Qin Donghui, Jeff Fergusson, Linlin Liu, John G. Emery, Sylvie Laquerre, Mui Cheung, Allen Oliff, Chengde Wu, Yan Pan, Zhiliu Zhang, Yan Chen
Publikováno v:
ACS Med Chem Lett
[Image: see text] We report herein the discovery of quinazolindiones as potent and selective tankyrase inhibitors. Elucidation of the structure–activity relationship of the lead compound 1g led to truncated analogues that have good potency in cells