Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeff Ecsedy"'
Autor:
Karen McGovern, Marta Sanchez-Martin, Jeremy H. Tchaicha, Jeff Ecsedy, Ben Amidon, X. Michelle Zhang, Alfredo C. Castro, Hyejin Frosch, Katie O'Callaghan, Sakeena Syed, Prabitha Natarajan, Jill Cavanaugh
Publikováno v:
Regular and young investigator award abstracts.
Background Aryl Hydrocarbon Receptor (AHR) is a transcription factor that regulates the activity of multiple innate and adaptive immune cells subsequent to binding to a diverse set of endogenous and exogenous ligands. One such endogenous AHR ligand i
Autor:
Silvia Coma, Jeremy H. Tchaicha, Jill Cavanaugh, Jeff Ecsedy, X. Michelle Zhang, Alfredo C. Castro, Mark Manfredi, Karen McGovern, Meghan Walsh, Marta Sanchez-Martin
Publikováno v:
Cancer Research. 79:4131-4131
Checkpoint inhibitors (CPIs) have become the cornerstone of immune-based oncology therapy; still many cancer patients do not benefit from these agents. Resistance to checkpoint inhibitors is due in part to the presence of immunosuppressive molecules
Autor:
Tilat A. Rizvi, Les Sprague, Keri A. Streby, Pin-Yi Wang, Duo Chen, Jeff Ecsedy, Joe Conner, Meghan Franczek, Katherine E. Chaney, Brooke Nartker, Nancy Ratner, Timothy P. Cripe, Ami V. Patel, Chun-Yu Chen, Mark A. Currier
Publikováno v:
Cancer Research. 76:B35-B35
We previously reported xenograft models of neuroblastoma and malignant peripheral nerve sheath tumor (MPNST) are responsive to direct intratumoral injection of oncolytic Herpes Simplex Viruses (Parikh et al., Ped Blood Can 44:469, 2005; Mahller et al
Autor:
Mark Currier, Tilat Rizvi, Brooke Nartker, Duo Chen, Pin-Yi Wang, Ami Patel, Katherine Chaney, Keri Streby, Balveen Kaur, Paola Grandi, Joseph Glorioso, E. Antonio Chiocca, Jeff Ecsedy, Joe Conner, Nancy Ratner, Timothy Cripe
Publikováno v:
Molecular Therapy. 23:S171
Neuroblastoma, a heterogeneous tumor that arises from the neural crest, is the most common extracranial solid tumor in children. Fewer than half of patients with high-risk features survive long-term, despite multi-modal therapy with surgery, chemothe
Autor:
Derek Blair, Jeff Ecsedy, Jerome T. Mettetal, Arijit Chakravarty, Patrick Vincent, Esha Gangoli, Wen Chyi Shyu
Publikováno v:
Cancer Research. 73:3411-3411
A mechanistic understanding of a drug's biological effect can have significant implications for selection of clinical dosing schedule, combination partners, as well as biomarker selection. In this context, a question often faced from target validatio