Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jeff Digre"'
Autor:
Ke Shi, Keun Seok Seo, Cathleen A. Earhart, Jeff Digre, Fikre Mengistu, C. Kent Brown, Douglas H. Ohlendorf, Patrick M. Schlievert, M. Huseby, Gregory A. Bohach
Publikováno v:
Journal of Bacteriology. 189:8719-8726
Beta toxin is a neutral sphingomyelinase secreted by certain strains of Staphylococcus aureus . This virulence factor lyses erythrocytes in order to evade the host immune system as well as scavenge nutrients. The structure of beta toxin was determine
The 3.35 A resolution crystal structure of a mutant form of the staphylococcal sphingomyelinase β toxin in which a conserved hydrophobic β-hairpin has been deleted is reported. It is shown that this mutation induces domain swapping of a C-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41062d0f49b103ee158fdcf53cc4c2cd
https://europepmc.org/articles/PMC3080144/
https://europepmc.org/articles/PMC3080144/
Autor:
Gregory A. Bohach, M. Huseby, Jeff Digre, Petra L. Kohler, Jillian A. Vocke, Douglas H. Ohlendorf, Ethan E. Mann, Kenneth W. Bayles, Patrick M. Schlievert, Cathleen A. Earhart, Andrew C. Kruse
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(32)
Biofilms are surface-associated communities of microbes encompassed by an extracellular matrix. It is estimated that 80% of all bacterial infections involve biofilm formation, but the structure and regulation of biofilms are incompletely understood.