Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jeff DeMartino"'
Autor:
Jeff DeMartino, Michael T. Meister, Lindy L. Visser, Mariël Brok, Marian J. A. Groot Koerkamp, Amber K. L. Wezenaar, Laura S. Hiemcke-Jiwa, Terezinha de Souza, Johannes H. M. Merks, Anne C. Rios, Frank C. P. Holstege, Thanasis Margaritis, Jarno Drost
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Paediatric rhabdomyosarcoma (RMS) is a soft tissue malignancy of mesenchymal origin that is thought to arise as a consequence of derailed myogenic differentiation. Despite intensive treatment regimens, the prognosis for high-risk patients re
Externí odkaz:
https://doaj.org/article/6e17129946ec4b3cabd8153ddce619c9
Autor:
Michael T Meister, Marian J A Groot Koerkamp, Terezinha de Souza, Willemijn B Breunis, Ewa Frazer‐Mendelewska, Mariël Brok, Jeff DeMartino, Freek Manders, Camilla Calandrini, Hinri H D Kerstens, Alex Janse, M Emmy M Dolman, Selma Eising, Karin P S Langenberg, Marc van Tuil, Rutger R G Knops, Sheila Terwisscha van Scheltinga, Laura S Hiemcke‐Jiwa, Uta Flucke, Johannes H M Merks, Max M van Noesel, Bastiaan B J Tops, Jayne Y Hehir‐Kwa, Patrick Kemmeren, Jan J Molenaar, Marc van de Wetering, Ruben van Boxtel, Jarno Drost, Frank C P Holstege
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 10, Pp 1-23 (2022)
Abstract Rhabdomyosarcomas (RMS) are mesenchyme‐derived tumors and the most common childhood soft tissue sarcomas. Treatment is intense, with a nevertheless poor prognosis for high‐risk patients. Discovery of new therapies would benefit from addi
Externí odkaz:
https://doaj.org/article/bfe59c6efb18489cb65ad4d76f02464c
Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation
Autor:
Gui-Wei He, Lin Lin, Jeff DeMartino, Xuan Zheng, Nadzeya Staliarova, Talya Dayton, Harry Begthel, Willine J. van de Wetering, Eduard Bodewes, Jeroen van Zon, Sander Tans, Carmen Lopez-Iglesias, Peter J. Peters, Wei Wu, Daniel Kotlarz, Christoph Klein, Thanasis Margaritis, Frank Holstege, Hans Clevers
Publikováno v:
Cell stem cell, 29(9), 1333-1345.e6. Cell Press
Cell Stem Cell, 29(12), 1718-1720. Cell Press
Cell Stem Cell, 29(12), 1718-1720. Cell Press
Opposing roles have been proposed for IL-22 in intestinal pathophysiology. We have optimized human small intestinal organoid (hSIO) culturing, constitutively generating all differentiated cell types while maintaining an active stem cell compartment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6b3a4a7a07934d4cb43c7ee02e1304
https://doi.org/10.1016/j.stem.2022.11.001
https://doi.org/10.1016/j.stem.2022.11.001
Autor:
Jeff DeMartino, Michael T. Meister, Lindy Visser, Mariël Brok, Marian J. A. Groot Koerkamp, Laura S. Hiemcke-Jiwa, Terezinha de Souza, Johannes H. M. Merks, Frank C. P. Holstege, Thanasis Margaritis, Jarno Drost
Publikováno v:
bioRxiv
BioRxiv
BioRxiv
Paediatric rhabdomyosarcoma (RMS) is a soft tissue malignancy of mesenchymal origin which is thought to arise as a consequence of derailed myogenic differentiation. Despite intensive treatment regimens, the prognosis for high-risk patients remains di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8bb156f85717f807999957a119c863
https://doi.org/10.1101/2022.07.15.497944
https://doi.org/10.1101/2022.07.15.497944
Autor:
Frank C. P. Holstege, Jarno Drost, Ruben van Boxtel, Marc van de Wetering, Jan J. Molenaar, Patrick Kemmeren, Jayne Y. Hehir-Kwa, Bastiaan B. J. Tops, Max M. van Noesel, Johannes H. M. Merks, Uta Flucke, Laura S. Hiemcke-Jiwa, Sheila Terwisscha van Scheltinga, Rutger R. G. Knops, Marc van Tuil, Karin P. S. Langenberg, Selma Eising, M. Emmy M. Dolman, Alex Janse, Hinri H. D. Kerstens, Camilla Calandrini, Freek Manders, Jeff DeMartino, Mariël Brok, Ewa Frazer-Mendelewska, Willemijn B. Breunis, Terezinha de Souza, Marian J. A. Groot Koerkamp, Michael T. Meister
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d6c1a1dd7c26ccd4397c1f88597b5e
https://doi.org/10.15252/rc.2022721694
https://doi.org/10.15252/rc.2022721694
Publikováno v:
Business Wire (English). 05/09/2024.
Publikováno v:
Entravision Communications Corporation MarketLine Company Profile. 7/25/2024, p1-20. 20p.
Autor:
Lin, Lin1 l.lin@hubrecht.eu, DeMartino, Jeff, Wang, Daisong, Son, Gijs J. F. van, Linden, Reinier van der, Begthel, Harry, Korving, Jeroen, Andersson-Rolf, Amanda, Brink, Stieneke van den, Lopez-Iglesias, Carmen2, Wetering, Willine J. van de, Balwierz, Aleksandra, Margaritis, Thanasis, Wetering, Marc van de, Peters, Peter J., Drost, Jarno, Es, Johan H. van, Clevers, Hans h.clevers@hubrecht.eu
Publikováno v:
Science. 10/27/2023, Vol. 382 Issue 6669, p451-458. 8p. 1 Color Photograph, 3 Diagrams.
Autor:
de Jonge, Wim J1 (AUTHOR), Brok, Mariël1 (AUTHOR), Lijnzaad, Philip1 (AUTHOR), Kemmeren, Patrick1 (AUTHOR), Holstege, Frank CP1 (AUTHOR) f.c.p.holstege@prinsesmaximacentrum.nl
Publikováno v:
Molecular Systems Biology. Oct2020, Vol. 16 Issue 10, p1-16. 16p.
Publikováno v:
Health & Medicine Week; 11/17/2023, p2344-2344, 1p