Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeff Bierwagen"'
Autor:
Katrin Laakmann, Jorina Mona Eckersberg, Moritz Hapke, Marie Wiegand, Jeff Bierwagen, Isabell Beinborn, Christian Preußer, Elke Pogge von Strandmann, Thomas Heimerl, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Sepsis is one of the leading causes of death worldwide and characterized by blood stream infections associated with a dysregulated host response and endothelial cell (EC) dysfunction. Ribonuclease 1 (RNase1) acts as a protective f
Externí odkaz:
https://doaj.org/article/7c0269688b8b458fb4d7267fe2e39b81
Autor:
Jeff Bierwagen, Marie Wiegand, Katrin Laakmann, Olga Danov, Hannah Limburg, Stefanie Muriel Herbel, Thomas Heimerl, Jens Dorna, Danny Jonigk, Christian Preußer, Wilhelm Bertrams, Armin Braun, Katherina Sewald, Leon N. Schulte, Stefan Bauer, Elke Pogge von Strandmann, Eva Böttcher-Friebertshäuser, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transported PAMPs. As important reside
Externí odkaz:
https://doaj.org/article/5ab97f46113346758e29ef1c0e67adfd
Expression of TMPRSS2 is up-regulated by bacterial flagellin, LPS, and Pam3Cys in human airway cells
Autor:
Marie Schwerdtner, Annika Skalik, Hannah Limburg, Jeff Bierwagen, Anna Lena Jung, Jens Dorna, Andreas Kaufmann, Stefan Bauer, Bernd Schmeck, Eva Böttcher-Friebertshäuser
Publikováno v:
Life Science Alliance. 6:e202201813
Many viruses require proteolytic activation of their envelope proteins for infectivity, and relevant host proteases provide promising drug targets. The transmembrane serine protease 2 (TMPRSS2) has been identified as a major activating protease of in
Autor:
Nora Honke, Jeff Bierwagen, Kim Ohl, Rainer Fischer, Joachim Peitz, Stefano Di Fiore, Stefan Wüller, Norbert Wagner, Anastasia Wiener, Klaus Tenbrock
Publikováno v:
Arthritis & Rheumatology. 66:470-478
Objective Interleukin-6 (IL-6) signaling plays an important proinflammatory role, but this role is restricted by regulatory mechanisms that, for example, reduce the cell surface availability of the signal-transducing chain of the IL-6 receptor, gp130
Autor:
Nora, Honke, Kim, Ohl, Anastasia, Wiener, Jeff, Bierwagen, Joachim, Peitz, Stefano, Di Fiore, Rainer, Fischer, Norbert, Wagner, Stefan, Wüller, Klaus, Tenbrock
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 66(2)
Interleukin-6 (IL-6) signaling plays an important proinflammatory role, but this role is restricted by regulatory mechanisms that, for example, reduce the cell surface availability of the signal-transducing chain of the IL-6 receptor, gp130. The aim