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pro vyhledávání: '"Jeff Adamo"'
Autor:
Ryan Swanson, John Marken, Davis Goodnight, Kimberly Wellman, Jeff Adamo, Emily Engelhart, Oliver Serang, Aditya Agarwal, Cameron Cordray, Samer Halabiya, Kyle Minch, Randolph Lopez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/21fbc0f2587d4b6a9e8c8ca185f63c57
Autor:
Ryan Swanson, Davis Goodnight, Jeff Adamo, Kyle Minch, Emily Engelhart, Randolph Lopez, David Younger
Publikováno v:
Cancer Research. 83:LB333-LB333
Here, we demonstrate a novel approach for generating affinity detuned cytokines that can be fused to antibodies for selective immune cell activation to improve anti-tumor responses and mitigate systemic toxicity. Although cytokine therapies have demo