Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jeff A. Regnis"'
Autor:
Christy L. Shaffer, Aruna Sannuti, Fred L. Johnson, William D. Bennett, Jeff A. Regnis, Kirby L. Zeman, Carla Foy, Jana G. Johnson
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 164:302-306
Previous studies show that uridine 5'-triphosphate (UTP), a P2Y(2) receptor agonist, is effective at acutely enhancing mucociliary clearance in healthy, nonsmoking adults. UTP solution for inhalation is being developed by Inspire Pharmaceuticals unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b537b9b2c4ccb3ac2aaa2b92dc0d298a
https://doi.org/10.1164/ajrccm.164.2.2008094
https://doi.org/10.1164/ajrccm.164.2.2008094
Publikováno v:
Experimental Lung Research. 26:149-162
Patients with cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) have been shown to have impaired large airway clearance of radiolabelled particles as measured by external gamma camera scanning up to 6 hours post deposition. Recent studies sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a04f6a3fb1051619454b7e906bfc4b
https://doi.org/10.1080/019021400269844
https://doi.org/10.1080/019021400269844
Autor:
Peter T. P. Bye, Jennifer A. Alison, Colin E. Sullivan, Jeff A. Regnis, Roger D. Adams, Peter M. Donnelly
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 158:1450-1458
There are no reports concerning the regulation of end-expiratory lung volume (EELV) and flow-volume relationships during upper limb exercise in health and disease. We studied EELV during such exercise in 22 adults with cystic fibrosis (CF) and nine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075b7cd45439b4a4f1d4e0e7057432ae
https://doi.org/10.1164/ajrccm.158.5.9710009
https://doi.org/10.1164/ajrccm.158.5.9710009
Autor:
Peter T. P. Bye, Jennifer A. Alison, Peter M. Donnelly, Roger D. Adams, John R. Sutton, Jeff A. Regnis
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 156:1541-1548
Physiological responses to upper limb exercise have not been well documented in patients with cystic fibrosis (CF). This is the first study to quantify ventilatory responses to supported incremental upper limb exercise in this patient group. Twenty-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2937a8590fdb3d0033cbb4e38a78ca9c
https://doi.org/10.1164/ajrccm.156.5.97-02034
https://doi.org/10.1164/ajrccm.156.5.97-02034
Publikováno v:
Critical Reviews in Physical and Rehabilitation Medicine. 9:1-33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81ead920ae5fc2533e277aa4c1085df1
https://doi.org/10.1615/critrevphysrehabilmed.v9.i1.10
https://doi.org/10.1615/critrevphysrehabilmed.v9.i1.10
Autor:
Kathe G. Henke, Jeff A. Regnis, Amanda J. Piper, Colin E. Sullivan, Sally Parker, Peter T. P. Bye
Publikováno v:
Chest. 106:1717-1724
Patients with cystic fibrosis (CF) often hypoventilate during sleep with marked falls in oxygen saturation (SaO2%). This occurs most commonly during REM sleep, when there is a reduction in rib cage excursion and a fall in end-expiratory lung volume (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b883681b81c743531d9ed1151dd14b7e
https://doi.org/10.1378/chest.106.6.1717
https://doi.org/10.1378/chest.106.6.1717
Publikováno v:
American Review of Respiratory Disease. 144:507-512
Changes in end-expiratory lung volume (EELV) during exercise in normal subjects and in patients with severe chronic obstructive lung disease have previously been examined. To date there are no studies that have examined the changes in EELV in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9645538bfefe73e13d25e7bc63728a5
https://doi.org/10.1164/ajrccm/144.3_pt_1.507
https://doi.org/10.1164/ajrccm/144.3_pt_1.507
Publikováno v:
American journal of respiratory and critical care medicine. 161(5)
The detailed mechanisms of oxygen-induced hypercapnia were examined in 22 patients during an acute exacerbation of chronic obstructive pulmonary disease. Ventilation, cardiac output, and the distribution of ventilation-perfusion (V A/Q ) ratios were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4787a5b405d294c4612c62574f92b410
https://pubmed.ncbi.nlm.nih.gov/11401898
https://pubmed.ncbi.nlm.nih.gov/11401898
Autor:
Peadar G. Noone, Kirby L. Zeman, Jeff A. Regnis, Malcolm King, Johnny L. Carson, Richard C. Boucher, William D. Bennett, Michael R. Knowles
Publikováno v:
American journal of respiratory and critical care medicine. 160(1)
Primary ciliary dyskinesia (PCD) is a genetic disease characterized by abnormal ciliary structure and function and impaired mucociliary clearance. Because patients with PCD use cough clearance as an airway defense mechanism, we tested the hypothesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2309a0f0a0812824bf7cf54bf15c2e
https://pubmed.ncbi.nlm.nih.gov/10390392
https://pubmed.ncbi.nlm.nih.gov/10390392
Publikováno v:
The American review of respiratory disease. 148(5)
The aim of this study was to determine the benefits of CPAP applied during exercise in patients with cystic fibrosis (CF). A total of 33 CF patients with a wide range of lung function were studied. Pulmonary function tests were measured at rest. Endu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7698127f3d68d369d3ced540c110593d
https://pubmed.ncbi.nlm.nih.gov/8239164
https://pubmed.ncbi.nlm.nih.gov/8239164