Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jeff A. Parrott"'
Publikováno v:
Molecular and Cellular Endocrinology. 172:213-222
The ability of gonadotropins to act on and regulate normal ovarian surface epithelial (OSE) cells and ovarian cancer cells was investigated. Bovine OSE was used as a model to study normal OSE. Results demonstrate that follicle stimulating hormone (FS
Autor:
Sergio R. Ojeda, Gregory A. Dissen, Diane F. Hill, Jeff A. Parrott, Michael K. Skinner, Maria E. Costa
Publikováno v:
Endocrinology. 141:4736-4750
TrkA, the nerve growth factor (NGF) tyrosine kinase receptor, is expressed not only in the nervous system, but also in nonneural cells, including discrete cellular subsets of the endocrine and immune system. In the rat ovary, trkA receptor abundance
Publikováno v:
Biology of Reproduction. 63:789-796
Greater than 95% of ovarian cancers originate in the epithelial cells on the surface of the ovary. The current study investigates the expression and action of transforming growth factor alpha (TGFa) in ovarian surface epithelium (OSE) and the underly
Publikováno v:
Endocrinology. 141:2532-2539
Ovarian tumors are primarily derived from the layer of epithelium surrounding the ovary termed the ovarian surface epithelium (OSE). Although extensive research has focused on established ovarian tumors, relatively little is known about the normal bi
Publikováno v:
Biology of Reproduction. 62:1600-1609
Greater than 95% of ovarian cancers originate from the epithelial cells on the surface of the ovary termed ovarian surface epithelium (OSE). A normal aspect of OSE function is repeated proliferation after ovulation, and this is postulated to be invol
Autor:
Michael K. Skinner, Jeff A. Parrott
Publikováno v:
Biology of Reproduction. 62:491-500
More than 95% of ovarian cancers originate from the epithelial cells on the surface of the ovary, which are termed ovarian surface epithelium (OSE). These OSE cells are modified peritoneal mesothelial cells separated from underlying ovarian surface s
Autor:
Jeff A. Parrott, Michael K. Skinner
Publikováno v:
Molecular Reproduction and Development. 55:55-64
Factors that control recruitment of theca cells from ovarian stromal-interstitial cells are important for early follicle development in the ovary. During recruitment, theca cells organize into distinct layers around early developing follicles and est
Autor:
Michael K. Skinner, Jeff A. Parrott
Publikováno v:
Endocrinology. 140:4262-4271
Initiation of folliculogenesis through the induction of primordial follicle development in the ovary has an important role in determining the fertility and reproductive fitness of most mammalian species. The factors that control this critical process
Autor:
Michael K. Skinner, Jeff A. Parrott
Publikováno v:
Biology of Reproduction. 59:553-560
Ovarian hormones (i.e., estrogen and LH) may promote folliculogenesis by regulating the local production of mesenchymal inducer proteins that mediate theca cell-granulosa cell interactions. Theca cells produce hepatocyte growth factor (HGF) that can
Autor:
Michael K. Skinner, Jeff A. Parrott
Publikováno v:
Endocrinology. 139:2240-2245
Interactions between mesenchymal-derived thecal cells and epithelial-derived granulosa cells are essential for follicular development in the ovary. These mesenchymal-epithelial cell interactions are in part mediated by keratinocyte growth factor (KGF