Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jeff, Hsu"'
Autor:
Matthew J. Reilley, Patricia McCoon, Carl Cook, Paul Lyne, Razelle Kurzrock, Youngsoo Kim, Richard Woessner, Anas Younes, John Nemunaitis, Nathan Fowler, Michael Curran, Qinying Liu, Tianyuan Zhou, Joanna Schmidt, Minji Jo, Samantha J. Lee, Mason Yamashita, Steven G. Hughes, Luis Fayad, Sarina Piha-Paul, Murali V. P. Nadella, Xiaokun Xiao, Jeff Hsu, Alexey Revenko, Brett P. Monia, A. Robert MacLeod, David S. Hong
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Background The Janus kinase (JAK) and signal transduction and activation of transcription (STAT) signaling pathway is an attractive target in multiple cancers. Activation of the JAK-STAT pathway is important in both tumorigenesis and activat
Externí odkaz:
https://doaj.org/article/f4f7c89c60164d3da2e398789b9d791f
Autor:
Peiwen Yu, Wei Xu, Peter Lamb, Lynne Bannen, Faming Jiang, Yong Wang, Theodore J. Yun, Kevin G. Leong, Sharon Wu, Grachelle Lorenzana, Eric N. Johnson, Joan Balayan, Levina Goon, Jeffrey Serrill, Colin Chong, Jeff Hsu
Suppl Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397e296aa945c0dc7ca03b45008f935f
https://doi.org/10.1158/1535-7163.22523475.v1
https://doi.org/10.1158/1535-7163.22523475.v1
Autor:
Peiwen Yu, Wei Xu, Peter Lamb, Lynne Bannen, Faming Jiang, Yong Wang, Theodore J. Yun, Kevin G. Leong, Sharon Wu, Grachelle Lorenzana, Eric N. Johnson, Joan Balayan, Levina Goon, Jeffrey Serrill, Colin Chong, Jeff Hsu
Suppl Figure 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11abf00dc1b285d0ca685009a76195d0
https://doi.org/10.1158/1535-7163.22523466.v1
https://doi.org/10.1158/1535-7163.22523466.v1
Autor:
Peiwen Yu, Wei Xu, Peter Lamb, Lynne Bannen, Faming Jiang, Yong Wang, Theodore J. Yun, Kevin G. Leong, Sharon Wu, Grachelle Lorenzana, Eric N. Johnson, Joan Balayan, Levina Goon, Jeffrey Serrill, Colin Chong, Jeff Hsu
Supplementary Figures and Tables with adjoining Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a3b7150645dcef50d576e7c00ae9d0
https://doi.org/10.1158/1535-7163.22523460
https://doi.org/10.1158/1535-7163.22523460
Autor:
Peiwen Yu, Wei Xu, Peter Lamb, Lynne Bannen, Faming Jiang, Yong Wang, Theodore J. Yun, Kevin G. Leong, Sharon Wu, Grachelle Lorenzana, Eric N. Johnson, Joan Balayan, Levina Goon, Jeffrey Serrill, Colin Chong, Jeff Hsu
Suppl Figure 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a427ac05eb98da2bbbbbdf27bc349b34
https://doi.org/10.1158/1535-7163.22523463
https://doi.org/10.1158/1535-7163.22523463
Autor:
Peiwen Yu, Wei Xu, Peter Lamb, Lynne Bannen, Faming Jiang, Yong Wang, Theodore J. Yun, Kevin G. Leong, Sharon Wu, Grachelle Lorenzana, Eric N. Johnson, Joan Balayan, Levina Goon, Jeffrey Serrill, Colin Chong, Jeff Hsu
Suppl Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a72e3a914e4798d0a4a8a8ccb80d330
https://doi.org/10.1158/1535-7163.22523469.v1
https://doi.org/10.1158/1535-7163.22523469.v1
Autor:
Peiwen Yu, Wei Xu, Peter Lamb, Lynne Bannen, Faming Jiang, Yong Wang, Theodore J. Yun, Kevin G. Leong, Sharon Wu, Grachelle Lorenzana, Eric N. Johnson, Joan Balayan, Levina Goon, Jeffrey Serrill, Colin Chong, Jeff Hsu
Suppl Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4e9d92f563f32c7a7034c20c66455c
https://doi.org/10.1158/1535-7163.22523472.v1
https://doi.org/10.1158/1535-7163.22523472.v1
Autor:
Sven Diederichs, David L. Spector, A. Robert MacLeod, Martin Zörnig, Matthias Groß, Marion Stentrup, Gayatri Arun, Alexey Revenko, Gene Hung, Youngsoo Kim, Jeff Hsu, Moritz Eißmann, Monika Hämmerle, Tony Gutschner
PDF file - 808K, Supplementary Figure S1: This figure depicts the impact of MALAT1 loss on gene expression, splicing and SR protein phosphorylation. Supplementary Figure S2: This figure describes the generation of MALAT1-Knockout A549 cells using an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afbc4564bc21b27b78e45fb6bc14a38
https://doi.org/10.1158/0008-5472.22399232.v1
https://doi.org/10.1158/0008-5472.22399232.v1
Autor:
Sven Diederichs, David L. Spector, A. Robert MacLeod, Martin Zörnig, Matthias Groß, Marion Stentrup, Gayatri Arun, Alexey Revenko, Gene Hung, Youngsoo Kim, Jeff Hsu, Moritz Eißmann, Monika Hämmerle, Tony Gutschner
XLSX file - 564K, Supplementary Table S1: This table lists 459 genes that show a differential expression upon loss of MALAT1 in A549 lung cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a784b8625ccd5d860935f5de5a1ed4c8
https://doi.org/10.1158/0008-5472.22399229.v1
https://doi.org/10.1158/0008-5472.22399229.v1
Autor:
Jeff Hsu, Colin Chong, Jeffrey Serrill, Levina Goon, Joan Balayan, Eric N. Johnson, Grachelle Lorenzana, Sharon Wu, Kevin G. Leong, Theodore J. Yun, Yong Wang, Faming Jiang, Lynne Bannen, Peter Lamb, Wei Xu, Peiwen Yu
Publikováno v:
Molecular cancer therapeutics.
The multi-receptor tyrosine kinase inhibitor XL092 has been developed to inhibit the activity of oncogenic targets, including MET, VEGFR2, and the TAM family of kinases TYRO3, AXL and MER. Presented here is a preclinical evaluation of XL092. XL092 ca