Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jef L. N. Wolfs"'
Autor:
Jef L. N. Wolfs, Frauke Swieringa, Edouard M. Bevers, Peter William Collins, Nadine J.A. Mattheij, Marion A.H. Feijge, Roger van Kruchten, Christine Saunders, Johan W. M. Heemskerk
Publikováno v:
Blood, 121(10), 1850-1857. The American Society of Hematology
Scott syndrome, a bleeding disorder caused by defective phospholipid scrambling, has been associated with mutations in the TMEM16F gene. The role of TMEM16F in apoptosis- or agonist-induced phosphatidylserine (PS) exposure was studied in platelets fr
Autor:
Kelly Mast, Edouard M. Bevers, Jef L. N. Wolfs, Marie-Claire Kleinegris, Ger H. Koek, Eveline H.C. Mestrom
Publikováno v:
European Journal of Pharmacology, 693(1-3), 1-6. Elsevier Science
Ribavirin in combination with interferon-alpha is the standard treatment for chronic hepatitis C, but often induces severe anemia forcing discontinuation of the therapy. Whereas suppression of bone marrow by interferon may impact on the production of
Autor:
Edouard M. Bevers, Jef L. N. Wolfs, Robert F. A. Zwaal, Krishnakumar Balasubramanian, Theo Lindhout, Alan J. Schroit, Otto Bekers, Paul Comfurius
Publikováno v:
Cellular and Molecular Life Sciences, 66(2), 314-23. Springer
The exposure of phosphatidylserine (PS) at the cell surface plays a critical role in blood coagulation and serves as a macrophage recognition moiety for the engulfment of apoptotic cells. Previous observations have shown that a high extracellular [K(
Autor:
Paul Comfurius, Robert F. Zwaal, Simone J. Wielders, John C. Giddings, Jef L. N. Wolfs, Theo Lindhout, Edouard M. Bevers
Publikováno v:
Blood. 108:2223-2228
The platelet procoagulant response requires a sustained elevation of the intracellular Ca2+ concentration, [Ca2+]i, causing exposure of phosphatidylserine (PS) at the outer surface of the plasma membrane. An increased [Ca2+]i also activates Ca2+-depe
Autor:
Jan T. Rasmussen, Theo Lindhout, Edouard M. Bevers, J. F. W. Keuren, Robert F. A. Zwaal, Jef L. N. Wolfs, Paul Comfurius
Publikováno v:
Cellular and Molecular Life Sciences. 62:1514-1525
Platelet procoagulant activity is mainly determined by the extent of surface-exposed phosphatidylserine (PS), controlled by the activity of aminophospholipid translocase and phospholipid scramblase. Here, we studied both transport activities in singl
Publikováno v:
Molecular Membrane Biology. 20:83-91
Publikováno v:
Molecular Membrane Biology. 20:83-91
Membrane-perturbing agents that cause transformation of biconcave erythrocytes into echinocytes or stomatocytes were used to investigate the influence of erythrocyte shape on the rate of Ca(2+)-induced scrambling of phospholipids. Erythrocytes were t
Publikováno v:
Molecular membrane biology. 20(1)
Membrane-perturbing agents that cause transformation of biconcave erythrocytes into echinocytes or stomatocytes were used to investigate the influence of erythrocyte shape on the rate of Ca(2+)-induced scrambling of phospholipids. Erythrocytes were t