Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Jeetain Mittal"'
Autor:
Dinesh Sundaravadivelu Devarajan, Jiahui Wang, Beata Szała-Mendyk, Shiv Rekhi, Arash Nikoubashman, Young C. Kim, Jeetain Mittal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Material properties of phase-separated biomolecular condensates, enriched with disordered proteins, dictate many cellular functions. Contrary to the progress made in understanding the sequence-dependent phase separation of proteins, little i
Externí odkaz:
https://doaj.org/article/d7c147d0edb14753a5f2739391073cd5
Publikováno v:
eLife, Vol 12 (2024)
The heterochromatin protein 1 (HP1) family is a crucial component of heterochromatin with diverse functions in gene regulation, cell cycle control, and cell differentiation. In humans, there are three paralogs, HP1α, HP1β, and HP1γ, which exhibit
Externí odkaz:
https://doaj.org/article/a61360c5ae484aeea7692ab33c9f782a
Autor:
Sayantan Chatterjee, Yelena Kan, Mateusz Brzezinski, Kaloian Koynov, Roshan Mammen Regy, Anastasia C. Murthy, Kathleen A. Burke, Jasper J. Michels, Jeetain Mittal, Nicolas L. Fawzi, Sapun H. Parekh
Publikováno v:
Advanced Science, Vol 9, Iss 4, Pp n/a-n/a (2022)
Abstract Formation of membrane‐less organelles by self‐assembly of disordered proteins can be triggered by external stimuli such as pH, salt, or temperature. These organelles, called biomolecular condensates, have traditionally been classified as
Externí odkaz:
https://doaj.org/article/2ed0ceb965274edb93b472693f67bc0f
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Theoretical schemes to predict colloidal crystals of arbitrary complexity are highly desirable. Here the authors develop a general approach based on symmetry and stoichiometric constraints that predicts the stability of multicomponent colloidal latti
Externí odkaz:
https://doaj.org/article/b055f347d8f54e339d1d20902752e896
Publikováno v:
ACS Central Science, Vol 5, Iss 5, Pp 821-830 (2019)
Externí odkaz:
https://doaj.org/article/12067f16c44a45bbadb010ded73e126b
Publikováno v:
ACS Central Science, Vol 4, Iss 5, Pp 534-542 (2018)
Externí odkaz:
https://doaj.org/article/61d54a20c56d4fcfba2eeef9f5e327cf
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005941 (2018)
Membraneless organelles important to intracellular compartmentalization have recently been shown to comprise assemblies of proteins which undergo liquid-liquid phase separation (LLPS). However, many proteins involved in this phase separation are at l
Externí odkaz:
https://doaj.org/article/ca83b1deab6d4627a512faf10112e1d5
Autor:
Shiv Rekhi, Dinesh Sundaravadivelu Devarajan, Michael P. Howard, Young C. Kim, Arash Nikoubashman, Jeetain Mittal
Publikováno v:
The Journal of Physical Chemistry B. 127:3829-3838
Interaction strength and localization are critical parameters controlling the single-chain and condensed-state properties of intrinsically disordered proteins (IDPs). Here, we decipher these relationships using coarse-grained heteropolymers comprised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9dc32f5c12cef119757b1c9b1bf219
https://doi.org/10.1021/acs.jpcb.3c00830
https://doi.org/10.1021/acs.jpcb.3c00830
Autor:
Priyesh Mohanty, Utkarsh Kapoor, Dinesh Sundaravadivelu Devarajan, Tien Minh Phan, Azamat Rizuan, Jeetain Mittal
Publikováno v:
Biochemistry. 61(22)
A variety of membraneless organelles, often termed "biological condensates", play an important role in the regulation of cellular processes such as gene transcription, translation, and protein quality control. On the basis of experimental and theoret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645bffbde65ff499699715fcc6aef47b
https://pubmed.ncbi.nlm.nih.gov/35802394
https://pubmed.ncbi.nlm.nih.gov/35802394
Publikováno v:
bioRxiv
The heterochromatin protein 1 (HP1) family is a crucial component of heterochromatin with diverse functions in gene regulation, cell cycle control, and cell differentiation. In humans, there are three paralogs, HP1α, HP1β, and HP1γ, which exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7010fd4bceeee25b33f4fe1ccfa86cb5
https://doi.org/10.1101/2023.05.28.542535
https://doi.org/10.1101/2023.05.28.542535
