Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Jeehyeon, Bae"'
Autor:
Hanyong Jin, Ji-Hyun Yeom, Eunkyoung Shin, Yoonjie Ha, Haifeng Liu, Daeyoung Kim, Minju Joo, Yong-Hak Kim, Hak Kyun Kim, Minkyung Ryu, Hong-Man Kim, Jeongkyu Kim, Keun P. Kim, Yoonsoo Hahn, Jeehyeon Bae, Kangseok Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Transfer RNA halves (tRHs) have various biological functions. However, the biogenesis of specific 5′-tRHs under certain conditions remains unknown. Here, we report that inositol-requiring enzyme 1α (IRE1α) cleaves the anticodon stem-loop
Externí odkaz:
https://doaj.org/article/b4210d4c73d54d008503e0bd9a448d77
Autor:
Junyoung Park, Yongyang Luo, Jin Woo Park, Song Hyun Kim, Ye Joo Hong, Younghyun Lim, Young-Jin Seo, Jeehyeon Bae, Sang Beom Seo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract DNA methylation is an epigenetic modification that regulates gene expression and plays an essential role in hematopoiesis. UHRF1 and DNMT1 are both crucial for regulating genome-wide maintenance of DNA methylation. Specifically, it is well k
Externí odkaz:
https://doaj.org/article/cbef63504c3545b4b0e91278987f92e5
Publikováno v:
Oncogenesis, Vol 10, Iss 7, Pp 1-12 (2021)
Abstract Interferon-inducible guanylate-binding proteins (GBPs) are well-known for mediating host-defense mechanisms against cellular pathogens. Emerging evidence suggests that GBPs are also implicated in tumorigenesis; however, their underlying mole
Externí odkaz:
https://doaj.org/article/5e0e58d5570c4faea9d6b711453d960b
Autor:
Hanyong Jin, Boeun Lee, Yongyang Luo, Yuri Choi, Eui-Hwan Choi, Hong Jin, Kee-Beom Kim, Sang Beom Seo, Yong-Hak Kim, Hyung Ho Lee, Keun Pil Kim, Kangseok Lee, Jeehyeon Bae
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The Ku complex, formed by XRCC5/6 heterodimer, binds to double strand break (DSB) ends, initiating non homologous end joining (NHEJ) and preventing homologous recombination (HR). Here, the authors reveal that FOXL2, a forkhead family transcriptional
Externí odkaz:
https://doaj.org/article/dc3287deb2f54cbfa67a690e448af5a2
Autor:
Minho Lee, Minkyung Ryu, Minju Joo, Young-Jin Seo, Jaejin Lee, Hong-Man Kim, Eunkyoung Shin, Ji-Hyun Yeom, Yong-Hak Kim, Jeehyeon Bae, Kangseok Lee
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009263 (2021)
Bacteria utilize endoribonuclease-mediated RNA processing and decay to rapidly adapt to environmental changes. Here, we report that the modulation of hns mRNA stability by the endoribonuclease RNase G plays a key role in Salmonella Typhimurium pathog
Externí odkaz:
https://doaj.org/article/072a8c48e9ad45429737aa77332e12c7
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Malignant melanoma, characterized by its ability to metastasize to other organs, is responsible for 90% of skin cancer mortality. To investigate alterations in the cellular metabolome and lipidome related to melanoma metastasis, gas chromato
Externí odkaz:
https://doaj.org/article/ac4a74d356524865b132a6c5478b24d6
Autor:
Yuri Choi, Yongyang Luo, Seunghwa Lee, Hanyong Jin, Hye-Jin Yoon, Yoonsoo Hahn, Jeehyeon Bae, Hyung Ho Lee
Publikováno v:
Nucleic Acids Research. 50:8929-8946
Although both the p53 and forkhead box (FOX) family proteins are key transcription factors associated with cancer progression, their direct relationship is unknown. Here, we found that FOX family proteins bind to the non-canonical homotypic cluster o
Publikováno v:
Chemistry – A European Journal. 29
Autor:
Jaeyeong Park, Eunkyoung Shin, Ji-Hyun Yeom, Younkyung Choi, Minju Joo, Minho Lee, Je Hyeong Kim, Jeehyeon Bae, Kangseok Lee
Publikováno v:
Journal of Microbiology. 60:128-136
Acinetobacter baumannii causes multidrug resistance, leading to fatal infections in humans. In this study, we showed that Lys AB2 P3-His-a hexahistidine-tagged form of an antimicrobial peptide (AMP) loaded onto DNA aptamer-functionalized gold nanopar
Publikováno v:
Angewandte Chemie. 135