Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jeehee Suh"'
Publikováno v:
Bulletin of the Korean Chemical Society. 33:2067-2070
Bio-Organic Science Division, KRICT, Yuseong, Daejeon 305-600, KoreaReceived March 2, Accepted March 14, 2012Key Words : Pyrazole, Microwave, Ligand free, Copper, N-ArylationPyrazole and its derivatives exhibit interesting chemicaland biological prop
Publikováno v:
Chemical Biology & Drug Design. 80:89-98
Biological evaluation of N-aryl-4-aryl-1,3-thiazole-2-amine derivatives was examined for anti-inflammatory activity in in vitro and in vivo assays. The thiazole compounds showed direct inhibition of 5-lipoxygenase (LOX) that is a key enzyme of leukot
Autor:
Chang-Woo Lee, Dae-Sik Lim, Byung-Jung Choi, Eunhee Kim, Woo Ho Kim, Jeehee Suh, Moon-Sun Jang, Jee-Won Sul, Su-Jin Lee, Nam-Soon Kim
Publikováno v:
Journal of Biological Chemistry. 283:32344-32351
This study reports that Aurora-A (Aur-A) phosphorylates Fas-associated factor-1 (FAF1) at Ser-289 and Ser-291. Forced expression of a FAF1 mutant mimicking phosphorylation at Ser-289 and Ser-291 (FAF1 DD), but not phosphorylation-deficient FAF1 (FAF1
Publikováno v:
Bulletin of the Korean Chemical Society. 25:1003-1008
A novel class of alkoxybenzylcyanoguanidine analogs as the inhibitors of restenosis was discovered, which showed the inhibitory effects on angiotensin II-induced cell proliferation, determined by [ 3 H]thymidine incorporation method. The compound, N'
Autor:
Hong Lim, Sun-Ok Kim, Byung Ho Lee, Sung-Eun Yoo, Dong Ha Lee, Ho Won Seo, Jeehee Suh, Kyu Yang Yi, Sun-Kyung Lee, Hwa Sup Shin, Nakjeong Kim
Publikováno v:
Journal of Medicinal Chemistry. 44:4207-4215
This paper describes the design, synthesis, and biological evaluation of a novel anti-ischemic compound, (2S,3S,4R)-N-(6-amino-3,4-dihydro-2-dimethoxymethyl-3-hydroxy-2-methyl-2H-benzopyranyl)-N'-benzyl-N"-cyanoguanidine (33), and the structure-activ
Publikováno v:
Chemical biologydrug design. 80(1)
Biological evaluation of N-aryl-4-aryl-1,3-thiazole-2-amine derivatives was examined for anti-inflammatory activity in in vitro and in vivo assays. The thiazole compounds showed direct inhibition of 5-lipoxygenase (LOX) that is a key enzyme of leukot
Publikováno v:
ChemInform. 24
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(22)
A series of 3-substituted-benzofuran-2-carboxylic esters was synthesized and evaluated for biological activity as ischemic cell death inhibitors in H9c2 cells and rat primary cardiac myocytes under conditions of oxygen and glucose deprivation. The in
Publikováno v:
ChemInform. 35
Autor:
Hong Lim, Sunkyung Lee, Byung Ho Lee, Kyu Yang Yi, Sun-Ok Kim, Soo-Kyung Kim, Sung-Eun Yoo, Ho Won Seo, Nak Jeong Kim, Jeehee Suh
Publikováno v:
ChemInform. 34
This paper describes the design, syntheses, and biological evaluations of novel ATP-sensitive potassium channel (K(ATP)) openers, benzopyranyl indoline and indole derivatives. Among those, two enantiomers of indoline-2-carboxylic ethyl esters (14, 18